Philadelphia Retina Endowment Fund

US Government As Represented by the Secretary of the Army

Leonid I Beresnev

Mikhail Alexseevich Vorontsov

Michael A DellaVecchia

Larry Donoso

Gary Cathcart

Matt Banta

Jennifer C Ricklin

Perinkulam Krishnaprasad

Eric W Justh

Systems for optical wavefront sensing and control based on a phase contrast Fourier domain filtering technique. Optically or electronically controlled phase spatial light modulators (SLM) are used as the Fourier domain filter. A direct adaptive-optic feedback system using the optical wavefront sensing systems. A differential Zernike filter is also disclosed.

Wavefront phase sensors using optically or electrically controlled phase spatial light modulators

A method for compensating an optic aberration of an eye comprising the steps of applying to the eye a measuring light beam formed of incoherent light to provide an applied incoherent measuring light beam. An image quality metric is determined in accordance with the applied incoherent measuring light beam and the aberration is compensated in accordance with said image quality metric. A perturbation is applied to the image quality metric to provide a perturbed image quality metric and a determination is made whether a predetermined image quality is obtained in accordance with the perturbed image quality metric. An incoherent source light is transmitted from an incoherent light source to a mirror and redirected from the incoherent light source to the retina of the eye using the mirror in order to provide the applied incoherent measuring light beam.

High-resolution retina imaging and eye aberration diagnostics using stochastic parallel perturbation gradient descent optimization adaptive optics

An ocular refractive alteration device is controlled to alter an ocular refractive lens according to an eye of a patient, including applying to the eye a measuring light beam formed of incoherent light to provide an applied incoherent measuring light beam and determining an image quality metric according to the applied incoherent light beam. The ocular refractive lens alteration device is controlled to alter the refractive lens according to the image quality metric. A method is set forth for locating a tumor in-an eye including applying to the eye a measuring light beam formed of incoherent light to provide an applied incoherent measuring light beam and determining a frequency distribution is also set forth the applied incoherent measuring light beam. The tumor is locating according to the frequency distribution.

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Columbia, MD, United States of America

Leonid I Beresnev