Uniroyal Chemical Company, Inc.

Leonid B Volodarsky

Stephen M Fagan

Vilen Kosover

A process is provided for the preparation of imidazoline derivatives such as imidazoline nitroxyls and 1-hydroxy imidazoline.

Process for the preparation of imidazoline nitroxyl

The present invention is directed to substituted tetrahydropyrimidine derivatives of the general formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6 and R.sup.7, which may be the same or different, are hydrogen or alkyl aryl, cycloalkyl, alkaryl, aralkyl or heterocyclic, or substituted derivative thereof, R.sup.6 or R.sup.7 can additionally be --OH or --NR.sup.8 wherein R.sup.8 is hydrogen, alkyl, aryl, cycloalkyl, alkaryl, aralkyl or heterocyclic, or substituted derivative thereof, or R.sup.6 and R.sup.7 together can be .dbd.O or .dbd.NOH, and any two R groups on the same or adjacent carbon atoms can be joined in a cyclic configuration, and X is oxyl or hydroxy, it being provided that at least one of R.sup.2 and R.sup.3 and at least one of R.sup.4 and R.sup.5 are other than hydrogen.

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Novosibirsk, Russia

Leonid B Volodarsky