G.d. Searle & Company

Duraclean International, Inc.

Leonard N Nysted

Raphael Pappo

An apparatus and method, particularly adapted to clean fabrics, is disclosed. The apparatus includes a generally hollow head having two foam mixing chambers in close proximity to a vacuum chamber. Foam is generated adjacent the fabric to be cleaned by admixing pressurized air and a liquid foam-producing agent in the two mixing chambers. The air pressure directs the foam from the second mixing chamber towards the fabric. Two screens are used to control the consistency and application of the foam. Suction is simultaneously provided in the vacuum chamber, so that the foam is rapidly and continuously recovered. A brush means is positioned between the second mixing chamber and the vacuum chamber to further agitate the foam and fabric to be cleaned, and to help create a partial pressure when the moving foam is applied to the surface of a fabric.

Apparatus and method for fabric cleaning with foam

The present invention relates to 5-fluoro-PGI.sub.2 derivatives of Formula I. These compounds are useful for the treatment of platelet dysfunction. Also disclosed is the process for preparing them and the appropriate intermediates.

5-fluoro-PGI.sub.2 compounds

5 Fluoro PGI compounds

Compounds of Formula I and II are useful as potent antiarrythmic agents without significant effect on cardiac output and blood pressure.

Aminoalkyl steroids

A nozzle and method for generating foam is disclosed which includes a nozzle body, a nozzle inlet, an orifice, a gas inlet, an impingement pin and a nozzle outlet. The nozzle body has upstream and downstream ends and an inner wall defining a passage within the nozzle body. The nozzle inlet at the upstream end of the nozzle body permits introduction of a liquid foam producing agent into the passage. The foam producing agent then passes through the orifice, thereby forming a stream. This stream is directed past the gas inlets in the nozzle body to aspirate gas into the passage. The stream then impinges against the impingement pin which is disposed transversely across the passage. At least the upstream half of the cross-section of the impingement pin is annular so that the impingement pin disrupts the flow of the stream and splits it into secondary streams. These secondary streams pass outwardly on each side of the impingement pin and diverge with respect to each other prior to being deflected inwardly off the inner wall of the nozzle body. The nozzle outlet comprises a transverse slot disposed parallel to the impingement pin so that a thorough mixing between the gas and foam producing agent is effected prior to discharge through the nozzle outlet as foam.

Nozzle and method for generating foam

The above-captioned compounds are produced from optionally substituted benzoin compounds by sequential reactions with trizincbismethylene dibromide, phosphorous trichloride and an appropriately substituted amine. The instant compounds are valuable as pharmacological agents as is evidenced by their anti-microbial, anti-arrhythmic, pepsin-inhibitory and anti-hypertensive activity.

N,N-Disubstituted 2,3-diphenylallylamines

Preparation and the analgesic, antiulcerogenic, hypolipemic, and antimicrobial activity of 6-(aminated methyl)-3.beta.-oxy-5.alpha.-(cholestane/stigmastane)-5,6-diols, salts thereof, and intermediates thereto are disclosed.

6-(Aminated

Preparation of analgesic, antisecretory, anti-ulcerogenic, hypolipemic, and antimicrobial 6-aminomethylated 3-oxygenated cholest-5-enes is disclosed.

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Highland Park, IL, United States of America

Leonard N Nysted