Ribogene, Inc.

Rugby-darby Group Companies, Inc.

Leonard Lachman

Arthur H Goldberg

This invention relates to a method for treating angina pectoris. Pursuant to this method, a .beta.-adrenergic-blocking agent is administered acutely to a person having angina to provide an essentially immediate, therapeutic amount of bioavailable blocking agent. The invention further relates to a method wherein the blocking agent is nasally administered for this purpose.

Treatment of angina pectoris

This invention relates to the treatment of tachyarrhythmias of supraventricular origin. This condition may safely be treated by nasal administration of a composition comprising propranolol dissolved in a pharmaceutically acceptable, aqueous-based carrier. A total dose of up to 20 mg of propranolol may be administered at one time.

Treatment of tachyarrhythmias of supraventricular origin

This invention relates to a method for treating classical migraine headaches. Pursuant to this method, a therapeutic amount of .beta.-adrenergic-blocking agent is administered to a person suffering a migraine attack promptly upon onset of aura. The invention further relates to a method wherein the blocking agent is nasally administered.

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Fort Salonga, NY, United States of America

Leonard Lachman