Johnson & Johnson Gmbh

Ortho Pharmaceutical Corporation

Other

Phio Pharmaceuticals Corp.

Rxi Pharmaceuticals Corporation

Leonard L Kaplan

George A Ziets

William R Levis

Norman A Levin

Nawaz Ahmad

Darius D Dubash

John G Callahan

The present invention relates to compositions and methods of treating warts and other human papilloma virus (HPV) skin infections. The present invention relates to compositions and methods of treating skin cancer.

Effective sensitizing dose of a gelled immunomodulating topical composition

Topical drug compositions, containing contact sensitizing agents as the active components of the subject patent compositions, can provide a pharmacological action that induces a delayed hypersensitization reaction resulting in stimulation of cell mediated immunity when applied to the skin. The preferred composition contains, but is not limited to, Diphenylcyclpropenone as a preferred embodiment of the class of contact sensitizing drugs applied to the skin in an optimally prepared pharmaceutical formulation with controlled absorption properties to reach the peripheral circulation resulting in increases in CD4&plus; helper T cells of benefit to immunocompromised patients.

Topical immunomodulating compositions for treatment of aids, Hepatitis B & C, other infectious diseases, and cancer

An antipruritic, astringent and anti-inflammatory composition is provided. The composition is useful in the treatment of hemorrhoid symptoms.

Hemorrhoidal compositions

A spermicidally active suppository comprising an alkylphenoxypolyethoxyethanol as the spermicide, a mixture of water-soluble polyethylene glycols as the suppository base, a mixture of an organic acid and an inorganic bicarbonate as the foaming agents and a mixture of an amphoteric surfactant and a water-soluble film-forming agent as the foam-stabilizing agent.

Vaginal suppository

A completely water soluble effervescent denture cleanser tablet containing both an enzyme and one or more active oxygen compounds. The enzyme in said tablet is resistant to premature inactivation by the oxidizing agents in the tablet during storage and in use and therefore has the added enzymatic cleansing power not possessed by conventional tablets containing only the active oxygen compounds. A method for preparing enzyme-containing denture cleanser tablets in which the activity of the enzyme is usefully retained is also described.

Enzyme and active oxygen containing denture cleanser tablet

A water-soluble effervescent, layered denture cleanser tablet containing one or more enzymes in one layer and one or more active oxygen compounds in the other layer and in which the enzyme layer is faster dissolving than the active oxygen layer and is substantially completely dissolved before the dissolution of the active oxygen layer reaches a level which would inactivate the enzyme.

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East Brunswick, NJ, United States of America

Leonard L Kaplan