Spf Innovations, LLC

Avco Corporation

Leon Mir

Gaston De Los Reyes

Robert T Kaiser

Richard A Curtis

A system, method and device are disclosed for bio-processing a feed stream and providing a constant output by operating a continuous single-pass tangential-flow process. The single-pass process provides high conversion concentration while operating at relatively low feed flow rates, and the process can also be used to provide constant output diafiltration.

Method and apparatus for the filtration of biological solutions

A hybrid diafiltration system includes an intermediate tank, a feed pump and a single-pass concentration (SPC) module, feed and product flow diverting valves to affect a multi-step concentration, wash and final-concentration process with fewer recirculation passes than conventional systems.

Hybrid diafiltration system and methods

A separation module and method are disclosed for processing a liquid sample and providing high conversion by operating a single-pass tangential-flow process without a recirculation loop. In one embodiment, the separation module includes three reservoirs and has at least one long, thin channel with a large ratio of channel membrane area to: channel void volume; volume of a sample feed reservoir; and volume of the feed sample. In another embodiment, the separation module includes two reservoirs and a hydrophobic vent. The single-pass process provides high conversion while operating with relatively low pressure sources.

Method and apparatus for the filtration of biological samples

A system, method and device are disclosed for bio-processing a feed stream providing a constant output by operating a continuous single-pass tangential-flow process. Embodiments are operated without large circulation pumps. Other embodiments use components which can be disposed after a single use. The system, method and device can also be used to provide constant output diafiltration.

Tangential flow filtration system

This invention is directed to a scheme for increasing the height of a ferrofluid column in a ferrofluid sink/float separator by judiciously locating the access openings into the column of ferrofluid so that said opening is on a predetermined air-ferrofluid interface to support a specific height of a ferrofluid column.

Materials handling apparatus for a ferrofluid sink/float separator

A method of separating non-magnetic particles of different densities by using a ferrofluid to produce levitation wherein compensation is made for the magnetic attraction or interaction of the particles by removing particles too small for the desired sharpness of separation or by maintaining the ratio of the interaction force to the separation force outside of theoretical limits.

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Brookline, MA, United States of America

Leon Mir