Becton Dickinson and Company Limited

Organogenesis, Inc.

Other

The Gillette Company

Leon M Wilkins

Timothy A Stevens

John M Janson

William J Lahm

Stephen C Conley

Alexander G Tschumakow

Jatinder Rana

Haeri Roh-Schmidt

Mary A Murray

Kevin W Gellenbeck

David J Fast

David W Krempin

Yumei Lin

Silvia R Da Costa

John F Rebhun

Eric J Roos

Karla Leum Stoner

Stephen R Watson

Ruben Chevere

Christopher O'Reilly

Disclosed herein are dietary supplement compositions and methods for increasing or stimulating bone growth, decreasing or preventing bone resorption, increasing bone strength, improving bone structure, and improving bone architecture comprising a first composition comprising a combination of at least two of: quercetin,sp.,sp. root, Siberian ginseng,, licorice, and ipriflavone, wherein the combination of the first composition increases bone morphogenic protein-2 gene, promoter or protein expression; and a second composition comprising an extract of pomegranate in combination with at least one of Siberian ginseng,, green tea,sp., grape seed, Dong Quai, and ipriflavone, wherein the combination of the second composition inhibits the expression of RANK-L.

Anti-resorptive and bone building dietary supplements and methods of use

A bioreactor has a base for defining a well, a dish with a membrane suspended in the base, and a lid with gas permeable membranes and self-sealing ports.

Culture dish and bioreactor system

Cell insert assembly

An assembly and components therefor are disclosed for use in the field of cell and tissue culture. The assembly includes a base having one or more wells, and a cell culture insert which is mountable to the base such that the bottom wall of the insert is suspended within the well. Each well has a generally rectangular configuration such that openings are provided at each corner of the well for introducing fluid to the well. A cover is provided for protecting the assembly and maintaining the position of the cell culture insert.

Culture vessel and assembly

Culture dish

This invention is directed to cryopreservation of cultured tissue equivalents made by in vitro technology. The invention involves immersing a cultured tissue equivalent in a cooled cryoprotectant solution, agitating the cryoprotectant solution and the immersed cultured tissue to achieve effective penetration of the cryoprotectant solution into the cultured tissue equivalent, and then freezing the cultured tissue at a high freezing rate. The cryopreserved cultured tissue equivalent may be stored for indefinite periods of time prior to use. The cultured tissue equivalent is an in vitro model of the equivalent human tissue, which, when retrieved from storage can be used for transplantation or implantation in vivo or for screening compounds in vitro.

Cryopreservation of cultured skin or cornea equivalents with agitation

A skin tanning composition comprising an effective amount of imidazole or an imidazole derivative in a dermatologically acceptable vehicle.

Skin tanning compositions containing imidazoles

Growing community of inventors

North Andover, MA, United States of America

Leon M Wilkins