Amersham Pharmacia Biotech Ab

Pharmacia Biotech Ab

Pvac Medical Technologies Ltd.

Termira Ab

Lennart Soderberg

Jan Bergstrom

Thomas Engstrand

Kristoffer Bergman

Tim Bowden

Rolf Berglund

Makonnen Belew

A composition for treating or preventing inflammatory-related conditions includes as an active principle a carrier which exhibits a plurality of a scavenger structure capable of mitigating the activity of a mediator of inflammatory-related conditions. The scavenger structure includes a nucleophilic center complying with the formula X(&#x2014;R&#x2033;&#x2014;)(&#x2014;R')Hwhere: a) Xis a single-bonded heteroatom selected amongst N, O and S and exhibits a free electron pair; b) m is 0 or 1 and n is 1 or 2; c) &#x2014;R&#x2033;&#x2014; is a bivalent organic group providing attachment to the carrier via one of its free valences and to Xat the other free valence; and d) R&#x2032;&#x2014; is a monovalent organic group attached to the Xvia its free valence. A method for treating or preventing inflammatory-related conditions in an individual suffering from such conditions includes: providing the composition; and contacting the mediator within or separate from the individual.

Active principle for mitigating undesired medical conditions

Process for, in layers of a porous matrix, exhibiting the groups A, introducing a functionality using a reagent I, introducing the functionality by a reaction with the groups A. The characterizing feature is that the matrix is contacted with a functional deficiency of reagent I and that conditions and reagent I are chosen so that the reaction between reagent I and the groups A is more rapid than diffusion of reagent I in the matrix.

Process for introducing a functionality

Process for chromatographic separation of peptides and nucleic acid, and

A liquid chromatographic system comprises at least two modules, at least one fluid flow line, and at least two connector devices provided along the flow line and respectively connecting the modules to the flow line. One of the two modules comprises a separation module and the other of the two modules comprises an ancillary module having a non-separation function. Each of the two modules includes at least one end connector fit into the respective connector device, and each end connector is adapted to interchangeably fit into either connector device.

Liquid chromatographic system

Growing community of inventors

Uppsala, Sweden

Lennart Soderberg