Cardiac Pacemakers, Inc.

Ortho-clinical Diagnostics, Inc

Lemont Baker

Donald Lee Hopper

Aaron R McCabe

Veerichetty A Kadhiresan

Richard Fogoros

James A Esler

Chie Kawahara

Jilliann G Fricke

Kenneth C Beck

Muhidin A Lelic

Kassity Yefei Liu

Muhidin Lelic

A physiological response to activity (PRA) during a subject's activities of daily living (ADL) can be used, such as to generate useful diagnostic information about the subject. This can involve using a template, such as an impulse response template. The technique can be used with an implantable or other ambulatory medical monitoring or therapy device, such as a cardiac function management device, or with a local or remote external interface device.

Kinetics of physiological response to activity during activities of daily living

Systems and methods for estimating caloric expenditure. The systems can include a physiological sensor to measure a patient's physical activity, and a posture sensor to measure the patient's posture. An estimated caloric expenditure can be calculated based on data from the physiological sensor and the posture sensor. For example, the estimated caloric expenditure can be calculated at least in part based on the posture data. For example, the estimated caloric expenditure can be validated based on the posture data.

Apparatus and method for calculating caloric expenditure using posture

A system includes an implantable medical device. The implantable medical device includes a control circuit and a motion sensing device. The motion sensing device is coupled to the control circuit, and the motion sensing device is configured to transmit signals to the control circuit. The control circuit is configured to identify one or more steps of a patient using the motion sensing device signal.

Implantable medical device configured as a pedometer

Apparatus and methods for calculating caloric expenditure using posture

An implantable cardiac device is configured and programmed to assess a patient's cardiopulmonary function by evaluating the patient's heart rate response. Such evaluation may be performed by computing a heart rate response slope, defined as the ratio of an incremental change in intrinsic heart rate to an incremental change in measured activity level. The heart rate response slope may then be compared with a normal range to assess the patient's functional status.

Cardiopulmonary functional status assessment via heart rate response detection by implantable cardiac device

This document discusses, among other things, a system including an implantable medical device. The implantable medical device includes a control circuit and a motion sensing device. The motion sensing device is coupled to the control circuit, and the motion sensing device is configured to transmit signals to the control circuit. The control circuit is configured to identify one or more steps of a patient using the motion sensing device signal.

An apparatus for determining the volume of liquid in a probe tip of an aspirating or dispensing probe, such as those used in a diagnostic analyzer, includes: two electrodes on opposite sides of the probe tip and the electrodes and liquid form a variable capacitor; a resistor; a voltage source and the electrodes and resistor are in electrical communication in at least one of series, parallel or series and parallel to form an RC circuit; and a microprocessor in electrical communication with the RC circuit for converting an electrical signal to a volume of liquid in the probe tip. In a preferred embodiment, the probe tip is separate from the probe and is adapted to be fitted on the end of a probe for aspirating and dispensing a liquid. In another preferred embodiment, the apparatus further includes a solenoid, and the voltage source, electrodes, resistor, and solenoid are in electrical communication in at least one of series, parallel or series and parallel to form an RLC circuit, and the microprocessor is in electrical communication with the RLC circuit for converting an electrical signal to a volume of liquid in the probe tip. The apparatus can be used with a liquid have a known or unknown dielectric constant and can be used to determine the presence of bubbles in the liquid.

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Raleigh, NC, United States of America

Lemont Baker