University of Connecticut

Carnegie Mellon University

Leila Daneshmandi

Cato T Laurencin

Reza Amin

Armin Tahmasbi Rad

Mu-Ping Nieh

Brian Holt

Stephen T Schmidt

Stefanie A Sydlik

Anne M Arnold

Described herein are apparati and methods for growing cells in a manner that mimics the native three-dimensional environment. Cell cultures grown in the apparatus can be screened for inhibition by specific chemotherapeutics or other drugs.

Multigel tumor-on-a-chip system

The disclosure provides porous scaffold that include a plurality of microspheres, where the microspheres include a biodegradable polymer blended with a graphene family material (GFM), micro spheres, and methods for making and using such scaffolds and microspheres.

Graphene composite matrices and uses thereof

Described herein are apparata and methods for growing cells in a manner that mimics the native three-dimensional environment. Cell cultures grown in the apparatus can be screened for inhibition by specific chemotherapeutics or other drugs.

A compound includes a polysaccharide moiety and one or more chelating agents. The one or more chelating agents are covalently bonded to the polysaccharide moiety. The polysaccharide moiety can include a glycosaminoglycan moiety, such as a hyaluronic acid polymer or a sulfated glycosaminoglycan moiety. The compound can be used to treat or prevent a disease or disorder in a patient with a metal implant. The compound reduces a concentration of metal particulates or metal ions in the subject.

Growing community of inventors

Manchester, CT, United States of America

Leila Daneshmandi