Melica Hb

Arexis Ab

University of Liège

Pig Improvement Company Uk, Limited

Capilet Genetics Ab

Seghers Gentec N.v.

University of Washington

University of Copenhagen

Dalgety Plc

Biocistronix Ab

Gentec N.v.

Funbogen Ab

Leif Andersson

Stefan Marklund

Graham Stuart Plastow

Michel Georges

Richard Wales

Carl-Henrik Heldin

Geert Spincemaille

Elisabetta Giuffra

Gerli Rosengren Pielberg

James Kijas

Anna Olegovna Golovko

Kjell Robert Johan Lennartsson

Gabriella Lindgren

Olwen Irene Southwood

Merete Fredholm

Alan Archibald

Patrick Chardon

Maika Malig

Carine D A Nezer

Gary Jon Evans

Bhanu Chowdhary

Lisa S Andersson

Claus Böttcher Jörgensen

Carina Danielle A Nezer

Maria Moller

Maria Johansson Moller

Sofia Mikko

Terje Raudsepp

Inger Edfors-Lilia

Goran Andersson

Pascale Le Roy

Nadine Buys

Christian Looft

Evan E Eichler

Ernst Kalm

Denis Milan

Anne Lunden

Susanna Cirera

Annie Robic

Claire Rogel-Gaillard

Kenneth William Siggens

Carl-Johan Rubin

John Huddleston

Nathalie Iannuccelli

Joel Gellin

Claus Bøttcher Jørgensen

Inger Edfors-Lilja

The present invention relates to methods for detecting a genetic deletion at the SHOX locus of a horse, where the presence of such a genetic deletion indicates that the horse is a carrier of disease-causing mutation that can lead to skeletal atavism. The invention further provides nucleic acid primers and probes for use in methods for detecting the presence or absence of disease-causing genetic deletion at the SHOX locus of a horse.

Diagnostic test for skeletal atavism in horses

The present invention provides methods for predicting the pattern of locomotion in a horse including the ability of a horse to use different gaits and the ability to trot at a fast speed. The methods comprise determining in a sample of DNA obtained from a horse the presence or absence of at least one genetic marker, wherein said at least one genetic marker is located on horse chromosome 23, said marker being associated with the ability to use different gaits. The invention further provides primers that amplify markers being associated with the ability to use different gaits and hybridization probes to detect markers being associated with the ability to use different gaits and the ability to trot at a fast speed.

Method to predict the pattern of locomotion in horses

This document relates to methods and materials for determining whether or not a horse contains a Grey allele. For example, diagnostic methods such as nucleic acid-based detection methods and materials such as nucleic acid probes and primer pairs that can be used to determine whether or not a horse contains a duplication in intron 6 of STX17 nucleic acid are provided. This document also relates to methods and materials for treating a mammal having or being likely to develop cancer (e.g., benign, malignant, or metastatic cancer). For example, methods and materials for treating cancer in a mammal by administering an agent having the ability to reduce expression of an STX17 polypeptide and/or an NR4A polypeptide (e.g., an NR4A1, NR4A2, or NR4A3 polypeptide) in the mammal are provided.

Methods and materials related to hair pigmentation and cancer

Methods and materials related to grey alleles

The present invention relates to a method for selecting a domestic animal having desired genotypic properties comprising testing the animal for the presence of a parentally imprinted quantitative trait locus (QTL). The invention further relates to the use of an isolated and/or recombinant nucleic acid comprising a QTL or functional fragment derived therefrom to select a breeding animal or animal destined for slaughter having desired genotypic or potential phenotypic properties. In particular, the properties are related to muscle mass, fat deposition, sow prolificacy, and/or sow longevity.

Selecting animals for parentally imprinted traits

Transgenic non-human animals that express the &#x3b3;3 subunit of PRKAG are described, as well as methods of using the transgenic non-human animals as models for improving treatment, prevention, or diagnosis of diseases related to energy metabolism, including obesity, dyslipidemia, insulin resistance syndrome, and type 2 diabetes.

Expression constructs expressing Prkag3

Identification of a pig as resistant or non-resistant to enterotoxigenic(ETEC). Particularly, there is provided methods, probes and DNA molecules involved in identifying a pig as resistant or non-resistant to ETEC. There is also provided methods for breeding pigs using the information of resistance/non-resistance, mixed boar semen, and methods for developing drugs to compensate for non-resistance to ETEC.

Porcine polymorphisms and methods for detecting them

The invention relates to methods to select animals, such as mammals, particularly domestic animals, such as breeding animals or animals destined for slaughter, for having desired genotypic or potential phenotypic properties, in particular, related to muscle mass and/or fat deposition lean meat, lean back fat, sow prolificacy and/or sow longevity. Provided is a method for selecting an animal for having desired genotypic or potential phenotypic properties comprising testing the animal, a parent of the animal or its progeny for the presence of a nucleic acid modification affecting the activity of an evolutionary conserved CpG island, located in intron 3 of an IGF2 gene and/or for the presence of a nucleic acid modification affecting binding of a nuclear factor to an IGF2 gene.

Selecting animals for desired genotypic or potential phenotypic properties

Variants of the gamma chain of vertebrate AMP-activated kinase (AMPK), as well as nucleic acid sequences encoding the variants and use thereof for the diagnosis or treatment of dysfunction of energy metabolisms.

Variants of the Gamma Chain of AMPX, DNA sequences encoding the same, and uses thereof

Methods for determining the KIT genotype of pigs are provided. These methods are useful in determining coat colour genotype, breed determination and for screening pigs to determine those likely to produce larger litters, and/or those less likely to produce large litters. Kits for use in such methods are also provided.

Methods

The present invention provides methods for analysing animal products. In particular methods for differentiating animal products on the basis of breed origin or validating an animal product are provided.

Methods for analyzing animal products

The present invention relates to a polypeptide which is a flavin-containing monooxygenase 3 (FMO3), wherein said FMO3 is a polypeptide comprising at least a sequence having at least 85% identity with the polypeptide sequence SEQ ID NO: 15, in particular to a polypeptide which is a functionally altered mutant of flavin-containing mono oxygenase 3 (FMO3) leading to a buildup of trimethylamine in an animal. Further, the invention relates to nucleic acid sequences encoding said polypeptide, and to the complements of such nucleic acid sequences. Such nucleic acid sequences and fragments thereof may be useful e.g. as primers. The invention further relates to various methods for determining the presence in e.g. a nucleic acid sample of a nucleic acid sequence encoding a mutated FMO3 polypeptide.

Detection of mutations

The invention relates to methods to select breeding animals or animals destined for slaughter for having desired genotypic or potential phenotypic properties, in particular related to muscle mass and/or fat deposition. The invention provides a method for selecting a pig for having desired genotypic or potential phenotypic properties comprising testing a sample from said pig for the presence of a quantitative trait locus (QTL) located at a Sus scrofa chromosome 2 mapping at position 2p1.7.

Transgenic mouse expressing Prkag3

Methods for determining coat color genotypes in pigs are provided. In particular, these methods are based on determining whether a mutation is/is not present at one or more exon/intron splice sites of the KIT gene. Kits for carrying out such methods are also described.

Methods for determining coat color genotypes in pigs

Growing community of inventors

Uppsala, Sweden

Leif Andersson