Midiagnostics Nv

Imec Vzw

Lei Zhang

Chengxun Liu

Tim Stakenborg

David Cheyns

There is provided an arrangement () which allows for mixing a first fluid with a second fluid at a predetermined volume mixing ratio in a capillary driven fluidic system. The arrangement () allows filling an initially empty mixing chamber () with the first fluid. The arrangement then allows emptying a predetermined fraction of the first fluid from the mixing chamber () such as to form an empty space in the mixing chamber (). The arrangement then allows filling the empty space of the mixing chamber () with the second fluid, thereby allowing a predetermined volume of the first fluid to mix with a predetermined volume of the second fluid over time.

Arrangement for mixing fluids in a capillary driven fluidic system

Example embodiments relate to microfluidic devices for controlling pneumatic microvalves. One embodiment includes a microfluidic device for independently controlling a plurality of pneumatic microvalves. The microfluidic device is couplable to a pressure source. The microfluidic device includes a first substrate. The microfluidic device also includes a flexible membrane covering the first substrate. Additionally, the microfluidic device includes a second substrate covering the flexible membrane. Further, the microfluidic device includes one or more fluidic channels at least partially defined in the first substrate. In addition, the microfluidic device includes a pressure couplable to the pressure source and branching into a plurality of pressure channels. Still further, the microfluidic device includes at least one pressure control switch per pressure channel.

Microfluidic device for controlling pneumatic microvalves

There is provided an arrangement in a capillary driven microfluidic system for dissolving a reagent in a fluid. The arrangement () comprises a channel () for receiving a fluid at a first end, a valve () arranged at a second end of the channel so as to control a flow of the fluid to stop as it reaches the second end of the channel, and an actuator () for opening the valve () a predetermined time after receipt of the fluid by the channel (). The arrangement further comprises one or more structures () for holding a dried reagent. The one or more structures () each has a width (W) which is larger than a width (W) of the channel (), and the one or more structures are coupled to a side wall of the channel such that the fluid is allowed to enter the one or more structures from the channel, dissolve the dried reagent held therein, and diffuse back into the channel.

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Leuven, Belgium

Lei Zhang