Ares Trading S.a.

Lei Tan

Martin T Chian

Yan Zhou

Daniel E Koppel

Alice Chen Kim

Peter Lorenzen

Shehua Shen

Vaishali Suraj

Kelly Athayde Wirka

Martin Chian

Alice A Chen Kim

Systems and methods for automated imaging and evaluation of image based features are disclosed herein. Method for automated imaging and evaluation of image based features can include receiving time-lapse images of at least one human embryo contained in a multi-well culture dish that can have a plurality of micro-wells. Image based features can be automatically generated from the time-lapse images of the human embryo. The image based features, which can include a cavitation feature, can be inputted into a classifier. The classifier can automatically and directly generate a viability prediction with the classifier from the image-based features.

Systems and methods for automated assessment of embryo quality using image based features

Methods, compositions and kits for determining the developmental potential of one or more embryos are provided. These methods, compositions and kits find use in identifying embryos in vitro that are most useful in treating infertility in humans.

Quantitative measurement of human blastocyst and morula morphology developmental kinetics

Systems and methods for generating a mask for automated assessment of embryo quality are disclosed herein. The method for generating a mask for automated assessment of embryo quality can include receiving an image, including a plurality of pixels, of a human embryo from an imaging system. A pixel can be selected and features of the selected pixel can be determined by generating a plurality of random boxes of random sizes and at random locations about the selected pixel. The selected pixel can be identified as one of: inside of a mask area; and outside of the mask area based on the determined features.

Systems and methods for generating a mask for automated assessment of embryo quality

Abnormal syngamy phenotypes observed with time lapse imaging for early identification of embryos with lower development potential

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Menlo Park, CA, United States of America

Lei Tan