Honeywell International Inc.

Novartis Ag

Shanghai Ennovabio Pharmaceuticals Co., Ltd.

Shanghai Haihe Pharmaceutical Co., Ltd.

Chinese Academy of Sciences

Emc IP Holding Company LLC

Baoshan Iron & Steel Co., Ltd.

Nutrition Science Partners Limited

Link USA International, Inc.

Ennovabio (zhejiang) Pharmaceuticals Co., Ltd.

Honeywell Safety Products Usa, Inc.

Lei Jiang

Wei Sun

John Jenkins

Yongjun Chen

Yuan Xu

Ke Shang

Feng He

Lei Liu

Yuan Mi

Fang Liang

Yao-Chang Xu

Jianwen Deng

Scott Hutt

Jian Ding

Meiyu Geng

Zhiyong Feng

Ji Yue Zhang

Huixin Wan

Jianhua Cao

Haixia Zhao

Zhi Qiao

Xueli Xu

Jianyong Shou

Danyi Wu

Shengyang Liu

Xiaoping Xie

Yue Ping Li

Yi Zhang

Chao Chen

Gang Liu

Min Huang

Michael David Shultz

Jianmei Fan

Christine Hiu-Tung Chen

Haibing Guo

Hongping Yu

Young Shin Cho

Zhengtian Yu

Haibing Deng

Chaohong Liu

Miao Dai

Guoliang Xun

Dyuti Majumdar

Jianke Li

Wen Peng

Mingwei Zheng

Xingnian Fu

Xiaoxia Yan

Wei Zhang

Chao Wang

Lei Li

Yi Chen

Bo Tong Liu

Wei-Guo Su

Jianhua Zhang

Feng Cao

Weihan Zhang

Jing Ai

Ji Yue (Jeff) Zhang

Qiangang Zheng

Bing Wang

Junyan Xu

Qingyun Jiang

Xianlei Fu

Xuxing Chen

Zhao Zhao

Xiong Li

Zhiyong Yu

Feifei Liu

Qianqian Shen

Yucai Yao

Shuai Tang

Ning Tan

Yuxing Zhang

Chuantao Zha

Shuyun Zhang

Lingling Xu

Caigen Huang

Junxiang Liu

Zhixiong Hou

Xudong Mao

Xian Jin

Huaqing Cai

Zhilong Weng

Hongqiang Wang

Xiaoli Lu

Yuanfang Xiong

Xiaojing Lan

Qiankun Jiang

The present invention provides preparation of a semicarbazide-sensitive amine oxidase inhibitor and use thereof. In particular, disclosed in the present invention are a compound as represented by formula I, or a stereoisomer or a racemate or a pharmaceutically acceptable salt of the compound. Also disclosed in the present invention is that the compound can inhibit semicarbazide-sensitive amine oxidase.

Preparation of semicarbazide-sensitive amine oxidase inhibitor and use thereof

A protection cup for a hearing protection device (HPD) is provided. The protection cup includes a plurality of fractal elements disposed on an inner surface of the protection cup.

Apparatuses, systems, and methods for increasing or manipulating noise attenuation in hearing protection device

A class of five-membered fused with six-membered heterocyclic compounds represented by formula I and a pharmaceutical composition, preparation, and an application thereof are disclosed. These compounds have TRK kinase inhibitory activity and can treat diseases related to TRK dysfunction.

Five-and-six-membered heterocyclic compound and use thereof as protein receptor kinase inhibitor

Provided are a preparation of semicarbazide-sensitive amine oxidase inhibitor and the use thereof. In particular, disclosed are a compound as shown in formula I, or a stereoisomer or racemate or pharmaceutically acceptable salt thereof. Also disclosed is that the above-mentioned compound can inhibit semicarbazide-sensitive amine oxidase.

Preparation of seimicarbazide-sensitive amine oxidase inhibitor and use thereof

Provided are a JAK kinase inhibitor, preparation and use thereof. In particular, provided is a compound of Formula I, wherein each group is as described in the specification. The compound has an excellent JAK inhibitory activity, and therefore can be used to prepare pharmaceutical compositions for the treatment of cancer and other diseases related to JAK activity.

Aromatic heterocyclic compound with kinase inhibitory activity

A high-performance thermoformed component provided with a coating, and a manufacturing method therefor. The thermoformed component comprises a substrate and a coating thereon. The substrate comprises the following ingredients in percentage by weight: 0.01-0.8% of C, 0.05-1.0% of Si, 0.1-5% of Mn, 0.001-0.3% of P, 0.001-0.1% of S, 0.001-0.3% of Al, 0.001-0.5% of Ti, 0.0005-0.1% of B, 0.001-0.5% of Nb, 0.001-0.5% of V, and the remainder being Fe and other unavoidable impurities. The appearance of the thermoformed component has no color difference and no mottling. The surface oxygen content of the thermoformed component is 0.1-20 wt. %, and the ratio of the standard deviation to the average value of the surface oxygen content satisfies: 0<standard deviation of oxygen content/average value of oxygen content ≤0.3. In the manufacturing method, a coated steel plate that has undergone heat treatment, transfer processing, and hot stamping is not treated with oil.

High-performance thermoformed component provided with coating, and manufacturing method therefor

A protection cup () for a hearing protection device (HPD) and a method for manufacturing a protection cup (). The protection cup () includes a plurality of fractal elements disposed on an inner surface () of the protection cup ().

Provided are a compound for the prevention and treatment of diseases associated with PD-L1, a preparation method therefor and use thereof. Specifically, provided are the compound of formula I, the stereoisomer and the racemate thereof, or pharmaceutically acceptable salts thereof, and also provided is an application thereof in the preparation of a drug for the prevention and treatment of diseases associated with PD-L1.

Compound having PD-L1 inhibitory activity, preparation method therefor and use thereof

Hearing protection device

Methods, apparatuses, and systems for detecting internal defects of a protective headgear are provided. An example apparatus may include a protective headgear, an actuator element integrated within the protective headgear, a sensor element integrated within the protective headgear, and a processor element electronically coupled to the actuator element and the sensor element. In some examples, the processor element is configured to cause the actuator element to generate a first ultrasonic wave, wherein the first ultrasonic wave is propagated in the protective headgear, and receive a first output from the sensor element in response to the first ultrasonic wave.

Method, apparatus and system for detecting internal defect in protective headgear

Disclosed herein are extracts ofhaving highly concentrated active ingredients, preparation methods and medical use for treating autoimmunity and inflammatory disease.

Extracts of, methods for preparation and use thereof

The present invention provides a pyrido five-element aromatic ring compound, and a preparation method therefor and a use thereof. The compound provided in the present invention has an inhibitory effect on wild-type and/or mutant EZH2, and is well positioned to become a novel anti-tumor drug or a drug for the treatment of autoimmune diseases.

Pyrido five-element aromatic ring compound, preparation method therefor and use thereof

Provided in the present invention are a compound having the effects of preventing and treating diseases related to IDH mutation, and a preparation method and use thereof. In particular, provided in the present invention are the compound as shown in formula (I), a stereoisomer, a racemic body or a pharmaceutically acceptable salt thereof, and the use thereof in preparing drugs for preventing and treating diseases related to IDH mutation 

Compound having mutant IDH inhibitory activity, preparation method and use thereof

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Shanghai, China

Lei Jiang