Leland Stanford Junior University

Lei Cai

Widya Mulyasasmita

Sarah C Heilshorn

A viscoelastic hydrogel based on a protein hetero-assembled with a polymer is provided. The protein cannot self-assemble with itself and the polymer cannot self-assemble with itself. The protein has a first association sequence (1stA) and a first spacer (1stSp). The polymer has a second association sequence (2ndA) and a second spacer (2ndSp). The first association sequence and the second association sequence are physically cross-linked to interact with each other with a 1:1 known and specific stoichiometry to form a three dimensional scaffold. The protein is represented by {1stA(1stSp)}1stA, where x is &#x2267;2, and the polymer is represented by {2ndA(2ndSp)}2ndA, where y&#x2267;2.

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Lei Cai