Chinese Academy of Sciences

East China University of Science and Technology

Lefu Lan

Feifei Chen

Jian Li

Wei Huang

Jin Zhu

Liyun Yang

Dongliang Guan

Shuaishuai Ni

Yifu Liu

Hanwen Wei

Fei Mao

Iiyun Yang

Lun Xiong

Baoli Li

Provided are a class of vancomycin derivatives with a structure as shown in the general formula below and pharmaceutically acceptable salts thereof, a preparation method, a pharmaceutical composition containing the compound thereof, and the use of these compounds in preparing drugs for treating and/or preventing bacterial infection diseases, in particular drugs for treating infection diseases caused by Gram-positive bacteria. 

Vancomycin derivative, preparation method, pharmaceutical composition and use thereof

Disclosed are benzoheterocyclic alkylamine compounds, or a pharmaceutically acceptable salt thereof, or a stereoisomer thereof, and a preparation method thereof, and use of the same in the manufacture of an antibacterial drug as an inhibitor of staphyloxanthin synthesis in. 

Benzoheterocyclic alkylamine compounds and use thereof

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Lefu Lan