Bayer Healthcare LLC

Sun Pharma Advanced Research Company Limited

Lee Wood

Simon James Smith

David Stuart Harris

Ben Arlett

Jonathan David Tuckwell

Robert Owen Kivlin

Peter Schwan

John Paul Palmer-Felgate

Chris Kadamus

Kevin George Skinner

Matthew Burgess Avery

Robert Dyer

Subhas Balaram Bhowmick

Prashant Kane

Abhijit Takale

Richard Francis Day

Satish Madhukar Gokhale

Jonathan Wilkins

Duncan Aleck Bishop

Ganesh Sangaiah

Ajay Nandgaonkar

Samantha Anne Musgrave

Becky Lynn Pilditch

Matthew David Allen

A reconstitution device having an opening surrounded by a neck, and a cap including a first end, a second end, and an inner bore having a central aperture. A stopper is positioned in the opening of the neck and includes a portion capable of being perforated. A plunger is located at the second end of the cap, is configured to slide along the inner bore of the cap, and includes a shaft extending downwardly in a direction towards the stopper and having a pointed end for piercing the stopper. A locking mechanism is located in the cap and includes an aperture. The locking mechanism is configured such that when the plunger is pushed downwardly the shaft is allowed to pass through the aperture, but when the plunger is pulled upwardly the second aperture changes shape such that the shaft cannot freely pass through the aperture.

Reconstitution device

A reconstitution device for storing a first component of a pharmaceutical preparation includes a receptacle, a cap having a first end secured to the receptacle, a second end, and an inner bore having a central aperture. The device further includes a stopper located between the receptacle and the cap, the stopper including a portion capable of being perforated. The device also includes a plunger secured to the second end of the cap, a locking mechanism located in the cap, and an actuating mechanism. The actuating mechanism may prevent the device from inadvertent activation.

The present invention relates to an inhalation-activatable device for administration of medicament in powder form to the respiratory system of a patient.

Inhalation device

Inhaler

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Bridgend, United Kingdom

Lee Wood