Sunovion Pharmaceuticals Inc.

Pgi Drug Discovery LLC

Lee W Herman

Michele L R Heffernan

Linghong Xie

Douglas F Burdi

Carrie A Bowen

Larry Wendell Hardy

Scott P Brown

Compounds of Formula I are described as are pharmaceutical compositions containing such compounds. Methods of treating neurological or psychiatric diseases and disorders in a subject in need are also disclosed.

Heteroaryl-isochroman compounds and uses thereof

Compounds of formula I: are disclosed, as are pharmaceutical compositions containing such compounds. Methods of treating neurological or psychiatric disorders in a patient in need are also disclosed. Such disorders include depression, bipolar disorder, pain, schizophrenia, obsessive compulsive disorder, addiction, social disorder, attention deficit hyperactivity disorder, an anxiety disorder, autism, a cognitive impairment, or a neuropsychiatric symptom such as apathy, depression, anxiety, psychosis, aggression, agitation, impulse control disorders, and sleep disorders in neurological disorders such as Alzheimer's and Parkinson's diseases.

Dual NAV1.2/5HT2a inhibitors for treating CNS disorders

Compounds and uses thereof

Growing community of inventors

Natick, MA, United States of America

Lee W Herman