Wyeth

Lee Erwin Schechter

Michael G Kelly

Wayne Everett Childers

Sharon J Rosenzweig-Lipson

Boyd Lynn Harrison

Gan Zhang

Byron Abel Bravo

Stacey J Sukoff Rizzo

Methods and compositions are provided for treating sexual dysfunction, e.g., sexual dysfunction associated with drug treatment, using 5-HTreceptor antagonists.

Serotonergic agents for treating sexual dysfunction

Bicyclic indolyl derivatives and compositions containing such compounds are disclosed. Methods of using the bicyclic indolyl derivatives and compositions containing such composition as serotonergic agents, such as in the treatment of depression and anxiety, are also disclosed. In addition, processes for the preparation of bicyclic indolyl derivatives are disclosed.

Bicyclic indolyl derivatives and methods for their use as serotonergic agents

Compounds of the formulahave a long duration of action and are useful for the treatment of chronic diseases resulting from the dysfunction of the serotonergic 5-HTsystem, such as schizophrenia and other psychotic disorders such as paranoia and mano-depressive illness.

Serotonergic agents with long-acting in vivo effects

Growing community of inventors

Toms River, NJ, United States of America

Lee Erwin Schechter