Cincinnati Children's Hospital Medical Center

Westfaelische Wilhelms-universitaet Muenster

Westfalische Wilhelms-universität Münster

Lee A Denson

Ardythe L Morrow

Bruce C Trapnell

Bruce Colston Trapnel

Kanji Uchida

Jan Däbritz

Diagnostic methods for assessing risk of or presence of inflammatory bowel disease in a patient based on glycosyltransferase or histo-blood group antigen signatures or a combination thereof. Also disclosed herein are prognostic methods for monitoring inflammatory bowel disease progression in a patient.

Use of glycans and glycosyltransferases for diagnosing/monitoring inflammatory bowel disease

Described are methods and compositions for evaluating the relapse risk n subjects having an inflammatory bowel disease (IBD). Some embodiments include selecting a treatment for an evaluated IBD relapse risk in a subject.

Methods and compositions for determining and treating relapse in inflammatory bowel disease

Disclosed are novel biomarkers and methods related to diagnostic tests for the detection and characterization of inflammatory bowel diseases, such as Crohn's disease and ulcerative colitis. In particular, the instant invention relates to novel biomarkers and methods of using such biomarkers to predict disease behavior and severity, to differentiate among disease types, and to optimize selection of treatment options in individuals suspected of having an inflammatory bowel disease.

Serological markers of inflammatory bowel disease phenotype and disease progression

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Wyoming, OH, United States of America

Lee A Denson