Leica Mikrosysteme Gmbh

European Molecular Biology Laboratory

Leica Instruments (singapore) Pte. Ltd.

Leander Gaechter

Reinhard Lihl

Martin Schorb

John Briggs

Thomas Pfeifer

Saskia Mimietz-Oeckler

Günther Bock

Patrick Szabo

A module for a microscope stand comprises a control device with at least one computer hardware component being configured to control the microscope stand. The module further comprises a locating device configured to interact with another locating device formed in a housing of the microscope stand for mounting the module at a predetermined installation site within the housing.

Microscope stand and module and housing therefor

The invention relates to a holding apparatus () for sample carriers () for use in cryomicroscopy, encompassing: a body having at least one sample carrier receptacle that comprises at least one sample carrier support surface against which at least one sample carrier () is abuttable; at least one first sample carrier holding means (); and at least one second sample carrier holding means () that is configured to impinge upon the sample carrier () with force against the first sample carrier holding means (); and to an arrangement having a manipulation container and such a holding apparatus (), and to methods for introducing and withdrawing a sample carrier ().

Holding apparatus for sample carriers, and method for introducing and withdrawing a sample carrier

In a light microscope () for cryomicroscopy, encompassing at least an objective () and a sample stage () having a cutout () for a coolable holder () for a sample carrier mount, the cutout () being covered by a cover (), the sample stage () is displaceable in two horizontal directions (). The cover () rests floatingly on the sample stage (), and the objective () passes through a cutout (), corresponding to the objective (), in the cover (). The method for cooling a holder () for a sample carrier mount in a light microscope () for cryomicroscopes, by means of a flow of liquid nitrogen through a cooling conduit (), open at at least one end, in the holder (), is notable for the fact that the quantity of liquid nitrogen is dimensioned so that all of the nitrogen is present in gaseous form at at least one open end () of the cooling conduit ().

Light microscope having a sample stage for cryomicroscopy

The invention relates to a sample transfer device () for reception of a sample, having a transfer rod () that is configured for reception of a sample holder, the sample holder to be arranged in a chamber () of the sample transfer device () for the purpose of transferring the sample to a processing unit or analytical unit (), at least one measurement device () for measuring a physical variable being arranged inside the sample transfer device ().

Sample transfer device

A loading station () for translocating a frozen sample for electron microscopy, encompassing a chamber (), open toward the top, that is fillable at least partly with a coolant, the chamber () comprising in its side wall at least two ports () each for different sample transfer devices (), the ports () permitting introduction of a frozen sample into the chamber () via a selected sample transfer device and withdrawal of a frozen sample from the chamber via a respective different sample transfer device; and wherein a receptacle () for at least two differently configured sample holders () is arranged in the chamber (), the at least two sample holders () being detachably fastenable to at least one of the sample transfer devices () for introduction of the frozen sample into the chamber () and for withdrawal of the frozen sample from the chamber ().

Loading station for transferring frozen samples at low temperatures

In a manipulation container () for cryomicroscopy, having at least one holder () for a sample carrier mount () and at least one manipulation opening () for manipulating sample carriers or sample carrier mounts (), the holder () for a sample carrier mount () is movable into a displacement path (), passing completely through the manipulation container (), of a displacement apparatus () for the sample carrier mount ().

Growing community of inventors

Oberriet SG, Switzerland

Leander Gaechter