Biocon Limited

Centro De Inmunologia Molecular

Centro De Immunologia Molecular

Biocon Limited & Centro De Immunologia Molecular

Centro De Inmunolgia Molecular

Laxmi Adhikary

Ramakrishnan Melarkode

Jose Enrique Montero Casimiro

Pradip Nair

Kedarnath Nanjund Sastry

Rolando Perez Rodriguez

Josefa Lombardero Valladares

Monalisa Chatterji

Sundaraj David Rajkumar

Hema Balasubramanian

Sanjay Tiwari

Shrikumar Suryanarayan

Anand Khedkar

Nitin Patil

Ramavana Gururaja

Dinesh Baskar

Ankur Bhatnagar

Saravanan Desan

Rakesh Bhaiyyaram Mendhe

Surekha K Prabhu

Harish Venkatraman Pai

Madhav Kulkarni

Madenahally Channabasappa Shivakumar

Prijyajit Sengupta

Kriti Shukla

Sunaina Prabhu

Rasika Venkataraman

Ashutosh Sudhir Naik

Meenakshi Sudhakaran

Shrivardhan Patil

Seija Rohil

Anushikha Thakur

Srivatsa Koduru

Krishnappa Mane

Phanichand Kodali

Jose Enrique Casimiro

Sheija Rohil

Madenahalli Channabasappa Shivakumar

M C Shivakumar

The present invention relates to a humanized IgG1 isotype anti-CD6 antibody (T1h) that binds to the Scavenger receptor cysteine-rich (SRCR) domain 1 (D1) of CD6 present on the surface of thymic epithelial cells, monocytes, activated T cells and a variety of other cells types.

Monoclonal antibody and a method thereof

The present invention discloses rapid and cost-effective method of de-glycosyation of a glycoprotein, wherein, glycoprotein is combined with anionic surfactant and reducing agent and non-ionic surfactant in order to obtain stable denatured glycoprotein. An endoglycosidase is further added to denatured glycoprotein to cleave N-linked glycans in order to obtain de-glycosylated protein. A rapid tool for assessing the protein conformation by partial de-glycosylation is also presented wherein the partial de-glycosylated protein is analysed using capillary electrophoresis (CE-SDS).

Rapid and efficient de-glycosylation of glycoproteins

The invention relates to peptide mass fingerprinting technique for the proteins such as Human insulin and insulin analogs. The insulin analogues can vary at least by one amino acid, which is elusive to distinguish by currently available analytical methods. The invention further allows sequence confirmation of the peptide wherein the run time of the method is forty minutes. This method could be applied for molecules up to 50 kDa.

Peptide mapping method for sequence identification of insulin and insulin analogues

The present invention relates to a method or process for controlling, inhibiting or reducing protein fucosylation in a eukaryote and/or eukaryotic protein expression system. Said method comprises carrying out the protein expression and/or post-translational modification in the presence of an elevated total concentration of manganese or manganese ions.

Methods for controlling fucosylation levels in proteins

The present invention relates to a method or process for controlling, inhibiting or reducing protein fucosylation in a eukaryote and/or a eukaryotic protein expression system. Said method comprises carrying out the protein expression and/or post-translational modification in the presence of an elevated total concentration of manganese or manganese ions.

The present invention discloses a new strain ofsp. BICC 7522, its variants or mutants and use of the strain for the production of macrolides, process of production and purification of macrolides.

[object Object]

The present invention discloses a new strain ofsp. BICC 7522, its variants or mutants and use of the strain for the production of macrolides, process of production and purification of microlides.

Growing community of inventors

Karnataka, India

Laxmi Adhikary