Smithkline Corporation

Lawrence William Chakrin

Kenneth M Snader

Chester Rhodes Willis

Chester R Willis

Pharmaceutical compositions comprising a substituted 4,6-dihydroxy-2H-pyran-2-one and methods of inhibiting the antigen-antibody reaction by administering said compositions.

Method of treating asthma with 4,6-dihydroxy-2H-pyran-2-ones

Pharmaceutical compositions comprising a substituted 3-cinnamoyl-2H-pyran-2,6(3H)-dione and methods of inhibiting the antigen-antibody reaction by administering said compositions.

Substituted 3-cinnamoyl-2H-pyran-2,6(3H)-diones

Substituted 2H-pyran-2,6(3H)-dione derivatives, pharmaceutical compositions comprising such derivatives and methods of inhibiting the antigen-antibody reaction by administering said compositions. The active ingredients are the products formed by the reaction of acetonedicarboxylic acid with acetic anhydride followed by reaction with an appropriate amine. Certain of the dione derivatives are novel compounds per se.

Substituted 2H-pyran-2,6(3H)-dione derivatives, pharmaceutical

Pharmaceutical compositions comprising a substituted 3-cinnamoyl-2H-pyran-2,6(3H)-dione and methods of inhibiting the antigen-antibody reaction by administering said compositions. Certain of the 3-cinnamoyl-2H-pyran-2,6(3H)-diones are novel compounds per se.

Growing community of inventors

Haddonfield, NJ, United States of America

Lawrence William Chakrin