American Cyanamid Company

Lawrence W Torley

Jeffrey B Medwid

Andrew S Tomcufcik

John P Dusza

Bernard D Johnson

Rolf Paul

Robert G Kelly

N-[3-[2-(1H-Imidazol-1-yl)ethoxy]phenyl]-4-(2-thienyl)-2-pyrimidinamine and pharmacologicaly acceptable salts, useful as antiasthma agents and treatment of allergic diseases and exhibiting improved bioavailability properties.

N-[3-[2-(1H-imidazol-1-yl)ethoxy]phenyl]-4-(2-thienyl)-2-pyrimidinamine

This disclosure describes novel 4,5,6-substituted-N-(substituted-phenyl)-2-pyrimidinamines having antiasthmatic activity.

4,5,6-substituted-N-(substituted-phenyl)-2-pyrimidinamines

This disclosure describes certain substituted piperazine-1,4-naphthalenediones useful as anti-asthmatic agents.

Substituted piperazine-1,4-naphthalenediones useful as anti-asthmatic

This disclosure describes novel substituted 2-phenyl-1H-benzimidazoles and 2-phenyl-1H-benzimidazole-4,7-diones and novel 5-chloro-6-(4-substituted-1-piperazinyl)-2,1,3-benzothiadiazole-4,7-diones ; all of which are highly active as anti-asthmatic and anti-allergic agents.

Substituted benzimidazoles and benzothidiazoles having anti-asthmatic

This disclosure describes novel 4,5,6-substituted-N-(substituted-phenyl)-2-pyrimidinamines having anti-asthmatic activity.

Substituted piperazine-1,4-naphthalenediones useful for treating asthma,

This disclosure describes novel 6-(4-substituted-1-piperazinyl)-5,8-quinolinediones, 7-(4-substituted-1-piperazinyl)-5,8-quinolinediones, and 6-(4-substituted-1-piperazinyl)-5,8-quinoxalinediones which possess activity as anti-asthmatic and anti-allergic agents.

Substituted quinoxalinediones and their methods of use

This disclosure describes novel 6-(4-substituted-1-piperazinyl)-5,8-quinolinediones, 7-(4-substituted-1-piperazinyl)-5,8-quinolinediones, and 6-(4-substituted-1-piperazinyl)-5,8-quinoxalinediones which possess activity an anti-asthmatic and anti-allergic agents.

Growing community of inventors

Washingtonville, NY, United States of America

Lawrence W Torley