Other

Curis, Inc.

Chektec Corporation

Lawrence I Kruse

Oivin M Guicherit

Shirley Ann Brunton

Sheldon E Broedel, Jr

The present invention makes available methods and reagents for modulating proliferation or differentiation in a cell or tissue comprising contacting the cell with a compound. In certain embodiments, the methods and reagents may be employed to correct or inhibit an aberrant or unwanted growth state, e.g., by antagonizing a normal patched pathway or agonizing smoothened or hedgehog activity.

Small organic molecule regulators of cell proliferation

The invention provides a method of treating or preventing a fungal infection comprising administering to a plant having a fungal infection a composition comprising an effective amount of a compound of formula I, wherein said compound is the following or an agriculturally acceptable salt of the following: ##STR1## The invention further provides such compounds and related methods.

Antimicrobial agent for agriculture

The invention provides a method of treating a fungal infection comprising administering to an animal having a fungal infection a composition comprising an infection treating effective amount of a compound of formula I, wherein said compound is the following or a pharmaceutically acceptable salt of the following: ##STR1## The invention further provides such compounds and related methods.

Growing community of inventors

Claremont, NH, United States of America

Lawrence I Kruse