Isense Corporation

Lawrence B Jansen

W Kenneth Ward

Ellen M Anderson

Richard G Sass

Mark Nynest

Kenneth W Ward

A method of creating an analyte sensor. The method starts with the step of providing an electrochemically active surface. Then, at least one nub made of dielectric material and extending transversely outwardly from the electrochemically active surface is created. A curable liquid is applied to the electrochemically active surface and the nub and is then cured. In this process, the nub, which could be one of several nubs, serves to support the liquid before and during the curing.

Method of constructing a biosensor

A method of measuring an analyte concentration in body fluid in an animal body having skin and subcutaneous soft tissue that includes body fluid. The method comprises, introducing a portion of an analyte-measuring device into the subcutaneous soft tissue. The analyte-measuring device includes an analyte sensing element, having a sharpened distal end to facilitate introduction into the animal body. Additionally the sensing element has an indicating electrode that is adapted to be activated by electric power and to form a raw analyte measurement, when it is activated and in contact with the body fluid, in less than two minutes. The sensing device further has a reference electrode and an electric power and display device that is adapted to mate to the analyte-sensing element. The power and display device activates the analyte-sensing element by applying electric power to it. The analyte-sensing element is introduced into the animal body and is activated by the electric power and display device, thereby causing the analyte-sensing element to form a raw analyte measurement. The power and display device forms and displays a second analyte measurement that is related to the raw analyte measurement, within two minutes of the analyte sensing element being introduced into the body.

Analyte sensor

An insertion device that includes an insertable portion adapted to be inserted into and retained in an animal body and an ex vivo portion that is adapted to be worn while the insertable portion remains inserted. The device further includes a trocar that is adapted to insert the insertable portion into the animal body. In addition, a cavity in the ex vivo portion is adapted to accept and retain the trocar after the insertable portion is inserted and a force application device is adapted to withdraw the trocar from the animal body and place it in the cavity.

Transcutaneous sensor insertion device

An insertable analyte needle sensor, comprising a set of fine wires positioned together and a dielectric material covering a substantial portion of the fine wires but defining an opening filled with at least one partially permeable membrane. The wires may be treated with a gas plasma to facilitate membrane adherence. One membrane layer may comprise sulphonated polyethersulphone coated with silane.

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Portland, OR, United States of America

Lawrence B Jansen