University of Minnesota

Lauri Lehto

Matthew D Johnson

Shalom Michaeli

Silvia Mangia

Julia Slopsema

Gregory F Molnar

John Thomas Vaughan

Simeng Zhang

Olli Gröhn

Olli Grohn

Artem Shatillo

Systems and methods are provided for neuromodulation with simultaneous stimulation and reception of neuronal response. A closed-loop control system provides the ability to modulate any combination of at least five parameters of stimulation (magnitude, frequency, amplitude, time, and phase) based on any combination of at least five parameters of received signals. The neuromodulation is well-suited for deep brain stimulation (DBS) applications.

System and method for feedback-driven neuromodulation

Described here are bioelectric modulation systems and methods for generating rotating or spatially-selective electromagnetic fields. A modulation system includes a multichannel electrode with independently controllable electrode channels that can be operated to generate rotating electromagnetic fields that stimulate cells regardless of their orientation, or to generate spatially-selective electromagnetic fields that preferentially stimulate cells oriented along a particular direction. The bioelectric modulation system may be implemented for stimulation of neurons or other electrically active cells. The bioelectric modulation described here may be used for a variety applications including deep brain stimulation (DBS), spinal cord and vagus nerve stimulation, stimulation of myocardial (heart) tissue, and directional stimulation of muscles.

Bioelectrical modulation using rotating or spatially-selective electromagnetic fields

Growing community of inventors

Minneapolis, MN, United States of America

Lauri Lehto