University of Washington

Institute for Research in Biomedicine

Philip Morris Products S.a.

Laurent Perez

David Baker

Antonio Lanzavecchia

Neil P King

Lance Joseph Stewart

Jessica Marcandalli

Brooke Fiala

Jorge Fallas

Karen Oishi

Yang Hsia

Rosa Cabrera

Brooke Nickerson

Fabio Talamo

Disclosed herein are nanostructures and their use, where the nanostructures include

Self-assembling protein nanostructures displaying paramyxovirus and/or pneumovirus F proteins and their use

Disclosed herein are nanostructures and their use, where the nanostructures include (a) a plurality of first assemblies, each first assembly comprising a plurality of identical first polypeptides; (b) a plurality of second assemblies, each second assembly comprising a plurality of identical second polypeptides, wherein the second polypeptide differs from the first polypeptide; wherein the plurality of first assemblies non-covalently interact with the plurality of second assemblies to form a nanostructures; and wherein the nanostructure displays multiple copies of one or more paramyxovirus and/or pneumovirus F proteins or antigenic fragments thereof, on an exterior of the nanostructure.

Growing community of inventors

Bellinzona, Switzerland

Laurent Perez