Institut National De La Sante Et De La Recherche Medicale

Centre Hospitalier Universitaire De Toulouse

Université Paul Sabatier (toulouse Iii)

Université De Nice Sophia Antipolis

Inserm (institut National De La Sante Et De La Recherche Medicale)

Laurent Martinez

Bertrand Perret

Annelise Genoux

Michele Trabucchi

Emanuela Repetto

The present invention concerns an in vitro method of diagnosis or prognosis of an atherosclerosis-related disorder by detecting a small Y RNA (s-RNY), as well as the use of an inhibitor of s-RNY as a medicament against atherosclerosis-related disorders. The invention also concerns a method for screening for a compound suitable for the treatment of an atherosclerosis-related disorder.

RNY-derived small RNAs as biomarkers for atherosclerosis-related disorders

The present invention relates to a method for assessing a subject's risk of having a cardiovascular disease comprising the step of measuring the level of IF1 in a body fluid sample obtained from said subject wherein the level of EF1 is negatively correlated with the risk of said subject of having cardiovascular disease.

Method for measuring the level of circulating inhibitory factor 1 protein in a subject measuring the level of circulating inhibitory factor 1 (IF1) protein in a subject

Method for assessing a subject's risk of having a cardiovascular disease

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Toulouse, France

Laurent Martinez