Devgen Nv

Laurent Kubler

Romaan Raemaekers

Pascale Feldmann

Geert Plaetinck

Nicole Damme

Thierry Andre Olivier Eddy Bogaert

Irene Nooren

Lies Degrave

Frederic Pecqueur

Els Van Bleu

Isabel Remory

Els Vanbleu

Thierry Bogaert

Geert Karel Maria Plaetinck

Frédéric Pecqueur

The present invention relates to methods for controlling pest infestation using double stranded RNA molecules. The invention provides methods for producing transgenic cells expressing the double stranded RNA molecules, as well as compositions and commodity products containing or treated with such molecules.

Methods for controlling pests using RNAi

The present invention relates to methods for controlling pest infestation using double stranded RNA molecules. The invention provides methods for making transgenic plants that express the double stranded RNA molecules, as well as pesticidal agents and commodity products produced by the inventive plants.

dsRNA as insect control agent

The present invention concerns methods for controlling insect infestation via RNAi-mediated gene silencing, whereby the intact insect cell(s) are contacted with a double-stranded RNA from outside the insect cell(s) and whereby the double-stranded RNA is taken up by the intact insect cell(s). In one particular embodiment, the methods of the invention are used to alleviate plants from insect pests. Alternatively, the methods are used for treating and/or preventing insect infestation on a substrate or a subject in need of such treatment and/or prevention. Suitable insect target genes and fragments thereof, dsRNA constructs, recombinant constructs and compositions are disclosed.

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Beynost, France

Laurent Kubler