Centre National De La Recherche Scientifique

Université Pierre Et Marie Curie (Paris 6)

Université Paris Diderot-Paris 7

Ecole Superieure De Physique Et De Chimie Industrielles De La Ville De Paris

Eurofins Millidrop

Sorbonne Université

Ecole Normale Superieure De Lyon

Etablissements J. Soufflet

Gold Standard Diagnostics Millidrop

Université Pierre Et Marie Curie

Universite Paris Cité

Paris Sciences Et Lettres

Millidrop Instruments Sas

Laurent Boitard

Jérôme Bibette

Nicolas Bremond

Jean Baudry

Denis Cottinet

Jerome Bibette

Klaus Eyer

Gaël Yvert

Jean-Marie Baudry

Julien Sylvestre

Jairo Garnica Rodriguez

Elisa Brambilla

Hicham Ferhout

Jairo Ivan Garnica Rodriguez

Larysa Baraban

Fabien Bertholle

Pascal Panizza

Antoine Serge Dominique Drevelle

Krzysztof Langer

Jaïro Garnica Rodriguez

Nicolas Pierre Bremond

Riccardo Balzan

Guilhem Chenon

Antoine Serge Drevelle

Arthur Goldstein

The present invention relates to a recovery system for drops comprising: a conduit for the circulation of a working fluid comprising a plurality of pockets that are isolated by separators, a recovery substrate comprising multiple compartments, a displacement device that is able to successively position the outlet of the conduit opposite at least two different compartments, a preparation device that is able to inject, into the conduit, an additional volume of separator fluid and an additional volume of carrier fluid, such that the volume of at least one separator is greater than or equal to a critical separation volume, and that the volume of at least one bubble formed by a pocket and a part of the separator is greater than or equal to a critical detachment volume.

Drop recovery system and associated method

The method for analysis and cell culture comprises the following steps:

Method for analysis and cell culture and an associated system

A process is provided for isolating and analyzing microorganisms contained in a sample by collecting a determined volume in a sample, the determined volume representing all or part of this sample, likely to contain at least one microorganism. The collected volume is then split up into a plurality of compartments having a culture medium, the volume of each compartment being smaller than 10 &#x3bc;L, each compartment being isolated from the other compartments and having no interface with the ambient atmosphere. At least one microorganism is incubated in the compartments for determined durations, and compartments are detected that contain at least one microorganism. The incubation may be extended after detecting compartments so that at least one microorganism having a defined quantity can be detected, and then the content of the detected compartments can be recovered. Finally, at least one functional parameter relative to a microorganism in the compartments is determined.

Process for the isolation and analysis of microorganisms contained in a sample

The present invention relates to a method for selecting and recovering products, comprising the following steps:

Method and system for recovering products from an emulsion

A method for monitoring a reaction and a reaction system are provided. The reaction system includes at least one vessel for the reaction medium, which is in fluid communication with an injection tube; at least one vessel for a carrier fluid that is immiscible with the reaction medium, which is in fluid communication with a reaction tube; the injection tube being mounted so as to lead into the reaction tube such that individual drops of the reaction medium can be injected into the reaction tube and into the immiscible carrier fluid, so as to form a train of reaction chambers; at least one detector for monitoring a reaction; a means for classifying the reaction chambers; and at least one means for recirculating reaction chambers in front of at least one detector for monitoring a reaction.

Method for monitoring a reaction and to reaction system for implementing same

The present invention discloses a method for fusing or contacting reactor and reagent droplets in a three-phase microfluidic or millifluidic system with one of the phases being continuous, in which the reagent droplet is injected in the droplet train before it coalesces or contacts with the reactor droplet. More specifically, the reagent droplet detaches from the reagent inlet before being in contact with the reactor droplet. The method of the invention involves two successive but not concomitant steps: first producing in the droplet train a droplet of a reagent which breaks-up from the reagent reservoir before the second step of merging. The invention also discloses a milli/microfluidic device whose equivalent circuit is represented on FIG.

Method for fusing or contacting reactor and reagent droplets in a microfluidic or millifluidic device

This method comprises bringing drops to be separated into contact with an interface () suitable for allowing an osmotic equilibrium between the content of each drop to be separated. The method comprises an osmotic flow between the drops (A) of the first group of drops through the interface () in order to modify the density of each drop (A) of the first group of drops and the separation of the drops (A,B) according to the density thereof or a combination of the density and the volume in order to isolate the drops (A) of the first group of drops from the drops (B) of a second group of drops.

Method for high-throughput screening of drops by osmotic exchange and density variation

A method for reading an emulsion () including droplets and a continuous phase surrounding the droplets, the method includes:

Method and device for reading an emulsion

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Paris, France

Laurent Boitard