Isochem

Snpe

Laurence Ferruccio

Jean-Pierre G Senet

Hubert Bonnard

Patricia P Gauthier

Charles-Henry Vincent

Dominique Gibert

Anne Marie Vitrant

Pierre-Yves Le Roy

Guyselaine Vergne

The invention relates to a process for the preparation of an &#x3c9;-benzyl ester of an amino diacid, characterized in that the amino diacid is reacted with a benzyl alcohol derivative of formula (I)in which the Rsubstituent or substituents, which are identical or different, represent a hydrogen atom, a Cto Calkyl group, a Cto Calkoxy group or a halogen atom and n is equal to 1, 2 or 3, in the presence of at least one mol per mole of the amino diacid of an alkanesulphonic acid, optionally in the presence of a solvent. The intermediate alkanesulphonates of the &#x3c9;-benzyl esters of amino diacids and the &#x3c9;-benzyl esters of amino diacids are obtained with a good yield and an excellent purity by virtue of this process.

Process for the preparation of &#x3c9;benzyl esters of amino diacids and of alkanesulphonates of these esters, and these alkanesulphonates

The invention relates to a process for the preparation of N,N&prime;-carbonylbislactams by reaction of phosgene with at least one lactam which is characterized in that the tertiary amine is chosen from the group consisting of non-nucleophilic aliphatic tertiary amines. N,N&prime;-Carbonylbislactams of high purity are thus obtained with good yields, both in the laboratory and on the industrial scale.

Process for the preparation of N,N&prime;-carbonylbislactams

The disclosure relates to a process for the synthesis of substituted or unsubstituted aliphatic, cycloaliphatic or araliphatic chloroformates by reaction of the corresponding alcohol with phosgene, diphosgene and/or triphosgene. The reaction is carried out under a pressure of between 15&times;10 Pa and 85&times;10 Pa and at a temperature of between &minus;30&deg; C. and &plus;50&deg; C. The process is particularly well suited to the preparation of menthyl chloroformate and benzyl chloroformate.

Process for the synthesis of aliphatic, cycloaliphatic or araliphatic chloroformates

The invention relates to a process for preparing carboxamide oximes of the formula (I): in which R.sup.1 represents an aryl or heteroaromatic group, and R.sup.2 and R.sup.3 represent a hydrogen atom or groups as defined in the description, characterized by the three following steps:

Growing community of inventors

Vert le Grand, France

Laurence Ferruccio