Regeneron Pharmaceuticals, Inc.

Lauren Gurski

Aris I Baras

Goncalo Abecasis

Giovanni Coppola

Kavita Praveen

Manuel Allen Revez Ferreira

Tanya Teslovich Dostal

Claudia Schurmann

Carmelo Romano

Meghan Drummond Samuelson

Ying Hu

Gaurang Patel

Giusy Della Gatta

Trikaldarshi Persaud

The present disclosure provides methods of treating subjects having hearing loss, methods of identifying subjects having an increased risk of developing hearing loss, and methods of detecting Kelch Domain Containing 7B (KLHDC7B) variant nucleic acid molecules and variant polypeptides.

Kelch domain containing 7B (KLHDC7B) variants and uses thereof

The present disclosure provides methods of treating patients having an ophthalmic condition, methods of identifying subjects having an increased risk of developing an ophthalmic condition, methods of detecting human angiopoietin like 7 (ANGPTL7) variant nucleic acid molecules and variant polypeptides, and ANGPTL7 variant nucleic acid molecules and variant polypeptides.

Treatment of ophthalmic conditions with angiopoietin-like 7 (ANGPTL7) inhibitors

The present disclosure provides methods of treating patients having an ophthalmic condition, methods of identifying subjects having an increased risk of developing an ophthalmic condition, methods of detecting human Son of Sevenless 2 (SOS2) variant nucleic acid molecules and variant polypeptides.

Treatment of ophthalmic conditions with son of Sevenless 2 (SOS2) inhibitors

Growing community of inventors

Tarrytown, NY, United States of America

Lauren Gurski