Societe Des Produits Nestle S.a.

Soceite Des Produits Nestle S.a.

Nestec S.a.

Laure Poquet

Heiko Oertling

Fabiola Dionisi

Stephane Duboux

Marie Noelle Horcajada

Stefan Palzer

Rachid Bel-Rhlid

Gerhard Niederreiter

Laurent Forny

Gary Williamson

Julien Philippe Nicolas Mahieux

Federico Mora

Bruno Edgar Chavez Montes

Kaori Minehira Castelli

Stéphane Duboux

Mathieu Renouf

A composition contains at least one probiotic or enzyme selected from the group consisting of (i) a probiotic having &#x3b2;-glycosidase activity or a &#x3b2;-glycosidase, (ii) a probiotic having esterase activity or an esterase, (iii) a probiotic having both &#x3b2;-glycosidase activity and esterase activity or an enzyme having both &#x3b2;-glycosidase activity and esterase activity, (iv) a first probiotic having &#x3b2;-glycosidase activity and a second probiotic having esterase activity, (v) a probiotic having &#x3b2;-glycosidase activity and an esterase, (vi) a &#x3b2;-glycosidase and a probiotic having esterase activity and (vii) a &#x3b2;-glycosidase and an esterase. The at least one probiotic can form one or more of oleuropein aglycone, elenolic acid, hydroxytyrosol acetate or hydroxytyrosol from oleuropein. The composition can comprise oleuropein. The composition can be for treating or preventing impaired mobility in an older adult; stimulating bone formation and/or inhibiting bone resorption; treating or preventing synovitis in an individual in need or at risk thereof or treating or preventing articular cartilage degradation subsequent to synovitis in an individual having or recovering from synovitis; or preventing or treating cartilage breakdown.

Bioconversion of oleuropein

The present invention relates generally to probiotics, in particular probiotics capable of bio-converting olive polyphenols. The invention relates to a method of selecting a probiotic strain or probiotic strain mixture. Further aspects of the invention include the use of a probiotic strain to increase the bio-efficacy of olive polyphenols and a composition comprising a probiotic strain for use in the potentiation of a therapeutic effect and/or a prophylactic effect of oleuropein.

Method of selecting a probiotic

The present invention provides a method for producing caffeine, wherein the method comprises: (a) combining a coffee extract comprising caffeine with an aqueous organic acid; (b) crystallizing the coffee extract and the aqueous organic acid so as to form caffeine-organic acid co-crystals in an aqueous phase; (c) separating the caffeine-organic acid co-crystals from the aqueous phase; and (d) extracting caffeine from the co-crystals obtained in step (c), wherein step (d) comprises placing the co-crystals in an aqueous solution so as to form a caffeine precipitate and a solution comprising the organic acid. Also provided is a method for producing a decaffeinated coffee extract comprising chlorogenic acids.

Caffeine production method

The present invention relates to a method of forming dihydroferulic acid comprising providing ferulic acid and incubating the ferulic acid with a bacterial preparation ofCNCM 1-1225 or a bacterial preparation of natural derivatives ofCNCM 1-1225. An aspect of the invention is a composition comprising dihydroferulic acid and a bacterial preparation ofCNCM 1-1225 or its natural derivatives. A further aspect of the invention is a composition comprising ferulic acid and a bacterial preparation ofCNCM 1-1225 or its natural derivatives for use in the treatment or prevention of metabolic disease. Further aspects of the invention are the use of a bacterial preparation ofCNCM 1-1225 or its natural derivatives; and a kit for preparing a food product.

Method of forming dihydroferulic acid

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Servion, Switzerland

Laure Poquet