Imperial Innovations Limited

Imperial College Innovations Limited

Laura Tornatore

Menotti Ruvo

Guido Franzoso

Caroline Minli Rachel Low

Catherine Jane Tralau-Stewart

Albert Andrzej Jaxa-Chamiec

Simona Maria Monti

Antonio Palumbo

Alberto Rocci

Antonio Palmubo

A method of measuring Gadd45&#x3b2; expression comprising the step of measuring Gadd45&#x3b2; expression levels in a sample of cells, for example CD 138 expressing cells, obtained from a subject known to have or suspected of having a haematological malignancy. Expression levels may be used in diagnosis, for example of multiple myeloma, in providing a prognosis, for example in a patient having multiple myeloma or in guiding selection of an appropriate treatment agent, especially a treatment agent comprising Gadd45&#x3b2; and or MKK7 inhibitors. Also datasets comprising measured expression levels from multiple subjects.

Method of diagnosis and prognosis

Compounds based around tetrapeptide, tripeptide and dipeptide moeties and corresponding peptiod moeties. Related methods and pharmaceutical compositions for use in treatment of cancer, inflammatory diseases, and other disorders.

Gadd45beta targeting agents

Growing community of inventors

London, United Kingdom

Laura Tornatore