The Ohio State University

North Carolina State University

Laura Kuo

Christian Melander

William M Huggins

In one aspect, the disclosure relates to compositions and methods for dispersing exitingbiofilms and inhibiting formation ofbiofilms. In various aspects, the disclosed compositions can be used in methods of treating a persistentinfection, including an asymptomatic infection. Such infections can colonize a variety of tissues, including the gall-bladder. Also disclosed are methods of treating typhoid fever. Also disclosed are methods for mitigating or preventing secondary outbreaks of typhoid fever by treating asymptomatic subjects who had been symptomatic for typhoid fever at a previous time. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

Growing community of inventors

Columbus, OH, United States of America

Laura Kuo