Johnson & Johnson Vision Products Inc.

Other

Johnson and Johnson Vision Care, Inc.

Laura D Elliott

Frank F Molock, Jr

Ivan M Nunez

James D Ford

Michele L Neil

Ivan M Nu Nez

The invention provides compositions for forming ocular devices which compositions contain latent UV absorbers. The compositions of the invention may be used to conveniently and efficiently produce ocular devices through UV initiated, free radical polymerization.

Ocular devices manufactured with free radical-polymerizable latent ultra-violet absorbers

Shaped hydrogel articles such as soft contact lenses are prepared by the steps of:

Method of forming shaped hydrogel articles including contact lenses

Method of testing inert displaceable diluents used in forming shaped hydrogel articles such as soft contact lenses prepared by the steps of:

Method of testing inert, displaceable diluents used in forming shaped

An ophthalmic lens, particularly a soft hydrogel contact lens, is disclosed. The lens can be derived from a crosslinked polymer made by reacting a hydrophilic monomer with a crosslinking amount of a polyfunctional compound containing a saccharide residue. The preferred hydrophilic monomer is actually a mixture of the following individual hydrophilic monomers: a) the reaction product of a free radical reactive monoisocyanate and a monoalkoxy polyalkylether, b) N,N-dimethylacrylamide, and optionally c)hydroxyethyl methacrylate. The preferred polyfunctional compound is a prepolymer derived from an alkoxylated glucose or sucrose. This prepolymer can be made by reacting glucose or sucrose, which has been ethoxylated or propoxylated, with a free radical reactive isocyanate which has been capped. The free radical reactive isocyanate can be capped by reacting it with a polyalkylether, such as polyethylene glycol, and then reacting this intermediate with a diisocyanate.

Polymeric ophthalmic lens with crosslinker containing saccharide residue

Hydrophilic contact lenses made using a crosslinking agent of the formula

Contact lenses with hydrophilic crosslinkers

The present invention provides soft contact lenses adopted for placement over the cornea or in the eye which have a high oxygen permeability, a low water content and excellent mechanical properties. Moreover, the lenses of the instant invention have excellent protein and lipid deposition resistance relative to conventional contact lenses. Such lenses having the properties mentioned above comprises a prepolymer which contains an alkoxylate glucoside that is derivatized with at least one polysiloxane compound. The prepolymer is then placed in a suitable mold and polymerized by exposure to ultraviolet light.

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Jacksonville, FL, United States of America

Laura D Elliott