Other

Leland Stanford Junior University

Respironics, Inc.

Medical Scientific, Inc.

Laughton E Miles

Charles H Rogers

Jianguo Sun

Arthur H Rogers

A positive airway pressure therapy management module includes a user interface, a controller and memory. The module may include ports that capture data from a PAP device and/or from sensors. The user interface may display information and questions, and may receive answers. The controller may store data while offline from the network, and may respond to requests over the network while online with the network. A software product includes instructions that, under control of a computer, perform steps for managing positive airway pressure therapy of a patient. A method for managing positive airway pressure therapy of a patient captures data and communicates the data over a network. The method may capture data from a PAP device and/or from sensors, display questions and receiving answers, and calculate indices and/or metrics, perform a pressure titration, and/or relay commands to a PAP device in response to commands from the network.

Positive airway pressure therapy management module

An improved inductive plethysmography sensor involving a conductor having alternating active and inactive segments. The active segments preferably have a narrow diamond shape which minimizes the possibility of artifact. Because of the conductor design, the sensors can be placed completely about the chest and abdomen with any overlap arranged so that active segments overlap inactive segments.

Respiratory inductive plethysmography sensor

Method and apparatus are provided for carrying out multiple simultaneous transfers of fluid. The method and apparatus are particularly directed toward immunoassays wherein immunologically active compounds, such as antigens and haptens, are detected through their associated antibodies. The device relies on the ability to transfer fluids, such as biological samples and reagents, between a reservoir and an associated receptacle. By providing a receptacle having a port at its lower end and which is otherwise hermetically sealed, such fluid transfer can be effected by immersing the port beneath the surface of the fluid in the reservoir and manipulating the pressure on the remaining surface area outside the port. The transfer of biological fluids at positive pressure provides enhanced fluids flow characteristics, particularly reduction or elimination of the tendency of these fluids to froth or bubble. Moreover, since the fluids can easily be manipulated, they can be agitated to speed up the reaction and reduce the overall reaction time and can be transferred from the reaction zone to allow interim measurements of the extent of reaction to provide for a rate mode assay. The method and apparatus also find use in preparing solid phase reagents for use in assay systems, as well as a highly accurate pipetting system in analytic applications not limited to immunoassays.

Method and apparatus for performing assays

Method and apparatus are provided for carrying out simultaneous multiple manipulations. The method and apparatus are particularly directed toward heterogeneous (two phases) immunoassays, particularly radioimmunoassay (RIA) and immunoradiometricassays (IRMA and 2-site IRMA). These assays are primarily concerned with the determination of antibodies and immunologically active compounds (antigens and haptens). The device has a plurality of syringes mounted so as to allow for simultaneous and identical movement of the syringe plungers. In addition, means are provided for mounting open tubes, which are employed as solid phase reagents, to the ends of the syringes for the aspiration and discharge of unknown samples, reagents and wash solutions. A reservoir is provided in an upper portion of the apparatus for receiving solutions or dispensing solutions to the syringes. Individual assays may be carried out by using a single syringe and carrying out the process steps by transfers of solutions through a hollow tube.

Multiple assay machine and method

An improvement is made in 2-site immunoradiometric assay wherein a single labelled antibody can be used to assay many different antigens.

Universal reagent 2-site immunoradiometric assay using labelled anti

An apparatus for conducting chemical assays features a coiled soft plastic tube as a reaction chamber. Along the length of the plastic tubing is a slit therein through which a needle-like member of a travelling dispenser injects samples to be analyzed. The injected samples may react with a reactant previously deposited in the interior of the plastic tube. The apparatus is applicable to carrying out radioimmunoassays.

Growing community of inventors

Stanford, CA, United States of America

Laughton E Miles