Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt.

Magyar Tudomanyos Akademia Kozponti Kemiai Kutato Intezete

Nitrokemia Ipartelepek

Borsodi Vegyi Kombinat

Mta Kozponti Kemiai Kutato Intezet

Nitrokaelepek

Chinoin Gyogyszer Rt

Laszlo Simandi

Gyorgy Lugosi

Gabor Besenyei

Lajos T Nagy

Eva Somfai

Istvan Jelinek

Janos Bodnar

Antal Simay

Csaba Soptei

Elemer Tomordi

Istvan Turcsan

Sandor Nemeth

Jozsef Dukai

Erzsebet E Dioszegine

Maria Belak

Istvan Tibor Toth

Tamas U Kallay

Vilmos Simonidesz

Erzsebet Szalay

Gyula Szilagyi

Ferenc Nagy

Peter Gyory

Maria Szabo

Zsuzsanna Nad

Istvan Szita

Ilona Santa Nee Singola

Marta Lugosi

Antal S May

Peter Viski

Gyula Pazmandi

Gyorgy Paszthy

Ilona Szigeti Nee Kiss

The invention relates to a process for preparing arylsulphonyl isocyanates of the general formula (I) ##STR1## and addition derivatives thereof--where in the formula the meaning of the substituents are as follows:

Process for preparing arylsulphonyl-isocyanates and addition derivatives

Process for the preparation of pharmaceutical compositions

The invention relates to a process for preparing sulphonyl-ureas of the general formula (I) ##STR1## wherein Ar.sub.1 represents a phenyl, naphthyl or thienyl group, the derivatives thereof substituted by C.sub.1-4 alkyl, C.sub.1-4 haloalkyl, (halo)alkoxycarbonyl, (halo)alkyloxy, nitro, cyano groups as well as by halogen atoms,

Process for preparing N-sulphonyl-ureas

The invention relates to a new process for preparing known thiolcarbamate esters of the general formula (I) ##STR1## wherein R.sup.1 and R.sup.2 stand independently for hydrogen or a straight or branched chain alkyl group containing 1 to 6 carbon atoms or an alkenyl group containing 2 to 6 atoms, or an alkyl group containing 1 to 6 or an alkenyl group containing 2 to 6 carbon atoms and mono- or polysubstituted by halogen, oxygen, sulphur and/or nitrogen; or

Process for preparing esters of thiolcarbamic acids

A process for the preparation of substituted urea derivatives, and compositions and concentrates for the same purpose are disclosed. According to the process the substituted urea derivatives of formula (I) ##STR1## wherein R is hydrogen, alkyl, aryl, cycloalkyl or aralkyl, R.sup.1 and R.sup.2 are hydrogen, alkyl, alkenyl, alkinyl, alkoxy, oxyalkyl, cycloalkyl, aralkyl, alkoxycarbonylalkyl, aryl or heteroaryl, or R.sup.1 and R.sup.2 together with the adjacent nitrogen atom may form a saturated or unsaturated heterocycle, or a condensed and/or substituted ring system, and said heterocycle or said condensed and/or substituted ring system may contain also a sulfo group, can be manufactured by reacting an amine of formula (II) ##STR2## with an N-carbamoyl-benzoic acid sulfimide derivative of formula (III) ##STR3## The disclosed N-acylating composition comprises of from 3 to 60% by weight, preferably of from 5 to 50% by weight sulfimide derivative of formula (III), of from 97 to 40% by weight, preferably of from 95 to 50% by weight solvent, and if desired, an organic or inorganic base. The disclosed N-acylating concentrate comprises of from 60 to 95.5% by weight N-acylating agent of formula (III) and of from 4.5 to 40% by weight additives.

Process for preparing substituted urea derivatives

The invention relates to a process for the preparation of carbamic acid phenyl esters of the formula (I) ##STR1## by acylating phenol derivatives of the formula (II) ##STR2## wherein R is alkyl having 1 to 8 carbon atoms, aryl, cycloalkyl having 5 or 6 carbon atoms, aralkyl having 7 to 16 carbon atoms which groups can be substituted by one or more alkyl groups,

Process for O-acylating phenol derivatives and acylating compositions

A process is disclosed for preparing a carbamic acid phenyl ester of the formula (I) ##STR1## wherein R is alkyl having 1 to 8 carbon atoms, aryl, cycloalkyl having 5 or 6 carbon atoms, or aralkyl having 7 to 16 carbon atoms, wherein the aryl, cycloalkyl or aralkyl is unsubstituted or substituted by at least one alkyl group having 1 to 8 carbon atoms;

Growing community of inventors

Budapest, Hungary

Laszlo Simandi