Chinoin Gyogyszer Es Vegyeszeti

Monsanto Europe S.a./n.v.

Alkaloida Vegyeszeti Gyar Rt.

Aklaloida Vegyeszeti Gyar Rt.

Alkaloida Vegyeszeti Gyar Tiszavasvari

Laszlo Litkei

Vilmos Galamb

Imre Gulyas

Agota Repasine Veres

Edit Fehervari

Laszlone Roka

Jozsef Neu

Laszlone Pethe

Fulgencio Powell Moreno

Jozsef Vigh

Jozsef Knoll

Janos Repasi

Sandor Makleit

Istvan Gyoker

Geza Kiss

Sandor Berenyi

Gyorgy Toth

Attila Zoltai

Sandor Elek

Terez Mile

Istvanne Koczka

Rezso Bognar

Istavanne Koczka

Reszo Bognar

Jan Os Repasi

A solid, non-hygroscopic salt of the Formula (I) ##STR1## wherein R.sup.1 is hydroxy or alkyl; A is C.sub.1 to C.sub.4 alkyl-amino or an amino-alkyl group containing a primary or a secondary amino group; and B is ammonium ion or an alkyl-substituted ammonium ion, which is substantially free of a diammonium salt ##STR2##

Non-hygroscopic monoammonium salts of phosphonic acids or phosphinic

A solid, non-hygroscopic salt of the Formula (I) ##STR1## wherein R.sup.1 is dydroxy or alkyl;

Non-hygroscopic monoammonium salts of phosphonic and phosphinic acids

A solid, non-hygroscopic salt of the Formula (I) ##STR1## wherein R.sup.1 is hydroxy or alkyl;

Azidoethylmorphine, a new 7,8-dihydroisomorphine derivative, has excellent antitussive effects without respiration depression.

7,8-Dihydroisomorphine derivative, namely azidoethylmorphine

A process for the preparation of pharmaceutically acceptable 3-protected derivatives of 6-deoxy-6-azido-14-hydroxy-7, 8-dihydroisomorphine, selected from the group which consists of 3-O-acetyl-6-deoxy-6-azido-14-hydroxy-7, 8-dihydroisomorphine, 3-O-tetrahydropyranyl-6-deoxy-6-azido-14-hydroxy-7, 8-dihydroisomorphine and 3-O-methylenemethoxy-6-deoxy-6-azido-14-hydroxy-7, 8-dihydroisomorphine, and the salts of these compounds which comprise the following steps:

6-Deoxy-6-azido-14-hydroxy-7,8-dihydroisomorphine or a pharmaceutically

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Tiszavasvari, Hungary

Laszlo Litkei