Novo Nordisk A/s

Lars Peter Klitmose

Jens Ulrik Poulsen

Christian Plambech

Jesper Peter Windum

Jens Aage Munk

Henrik Ljunggreen

John Oestergaard Madsen

Preben Broskov Nielsen

Henrik Sune Andersen

Claus Schmidt Moller

Andre Larsen

Claus Schmidt Møller

Jim Radmer

Bennie Peder Smiszek Pedersen

Lars Hofmann Christensen

Kristian Glejbøl

Michael Ejstrup Hansen

Ebbe Kiilerich

Henning Munk Ejlersen

Peter Lundholm Jensen

Claus Urup Gjoedesen

So Slashedren Mikkelsen

Henrik Egesborg Hansen

Kim Ejholm Hansen

Anders Heger

Nicolai Michael Jensen

Dennis Bo Hansen

Steffen Mews

Salim Bouaidat

John Thrane Hansen

Soren Mikkelsen

Jens Mo slashedller-Jensen

Jacob Sonnerup Moellebro

Soren Kragh Jespersen

John ØStergaard Madsen

Jacob Sonnerup MØLLEBRO

Claus Urup GJØDESEN

A drug delivery device comprises a housing () and an expelling assembly with a piston rod (), a drive tube () with an outer surface and a scale drum () arranged between the drive tube and the housing, the scale drum being coupled to the housing and the drive tube outer surface. The device further comprises a drive spring () arranged between the housing and the drive tube, and setting means () allowing a user to simultaneously set a dose amount to be expelled and strain the drive spring correspondingly by rotation of the drive tube. The scale drum is coupled to the drive tube via a spline connection, wherein the drive spring is arranged proximally of the spline connection when the spline connection is in its proximal-most position.

Drug delivery device with slim drive mechanism

A geared drive arrangement comprises a stationary portion and a drive rod defining a reference axis and during operation being arranged to rotate and be moved axially corresponding to the reference axis, the drive rod comprising a first thread and a second thread. The drive arrangement further comprises a drive member comprising a drive thread in engagement with the drive rod first thread, and a nut portion comprising a propulsion thread arranged rotationally locked relative to the stationary portion and in engagement with the drive rod second thread. The drive member is arranged to rotate corresponding to the reference axis during operation, with the threaded engagement between the drive member and the drive rod causing the drive rod to rotate, and the threaded engagement between the nut portion and the drive rod causing the drive rod to move in the distal direction.

Drive arrangement with rotationally geared drive rod

A sensor assembly comprising a first rotary sensor part having a plurality of individual electrically conducting code segments arranged in a circumferential pattern, and a plurality of electrically conducting reference segments between the code segments, and a second rotary sensor part arranged rotationally relative to the first part a plurality of contact structures, each contact structure being arranged to be in contact with either a code segment or a reference segment depending on the rotational position between the first and second rotary sensor part. The contact structures are configured to engage and connect to different sensor segments as the first and second rotary sensor part rotate relative to each, the created connections being indicative of a rotational position between the first and second rotary sensor part. For a given rotational position, at least one contact structure engages a code segment and at least one contact structure engages a reference segment.

Rotary sensor assembly with space efficient design

A portable pen-type drug injection device () comprises a main portion () and a clip (). The clip comprises a base portion mounted to a portion of the drug delivery device, and a clip gripping portion with a free end. The device further comprises drug expelling means having dose setting means () allowing a user to set a dose of drug to be expelled, and a piston rod adapted to move a piston of a loaded cartridge in a distal direction to thereby expel drug from the cartridge. Electronic circuitry comprises sensor means adapted to detect a set and/or an expelled dose, and a display () is provided to display dose-related values, wherein at least a portion of the display is arranged in the flexible clip main portion.

Pen-type drug delivery device with electronic display on clip member

The present invention relates to an electronically assisted injection device adapted to inject doses of a drug from a held cartridge. The injection device may include a first rotational sensor () coupled to a driver () for sensing a dose setting and a second rotational sensor () coupled to a dosing member () for sensing an expelled dose. A third axial sensor () provides information relating to the axial position of the driver (). A control circuit is adapted to determine the end of dosed state based on data from the first, the second and the third sensors (). The injection device may also include an arrangement for determining fluid ingress into the interior of the injection device. The arrangement includes an electrically non-conductive surface portion () disposed on a first component () and an electrode assembly () disposed on a second component () wherein the first component () and the second component () moves relative to each other during operation.

Injection device incorporating dose monitoring

A RFID comprising a value sensor such as a pressure sensor is integrated with a liquid drug container to enable wireless pressure or other drug relevant parameter value monitoring and code-matching of drug container to a medical delivery device.

Medical device with value sensor

The invention relates to an injection device for injecting a dose of drug. The injection device comprises a housing, a dose setting mechanism being operable to set a desired dose, an injection mechanism comprising a piston rod () adapted to cooperate with a piston positioned in a cartridge containing a drug to be delivered in order to cause a set dose to be delivered from the cartridge via the injection device, a dosage tube (), and retaining means arranged to prevent axial movement of the dosage tube in a distal direction relatively to the housing during dose setting. The dose setting mechanism comprises a rotatable dose knob (), operation of the dose setting mechanism causing energy to be stored in a spring member. The injection mechanism is driven by releasing energy previously stored in the spring member during dose setting.

Injection device comprising a locking nut

This invention relates to a safety system for an electrically driven medical delivery device for delivering a dose of medication, wherein the safety system is configured for preventing delivery of an erroneous dose of the medicament and comprising detector means for registering mechanical movement, the system comprising at least two detector means () for detecting a mechanical parameter and for emitting signals to control circuits () configured for controlling the rower supply to driving means () for the delivery device. Further, this invention relates to a computer-readable medium comprising a program for controlling a delivery device etc. This allows providing a system that works very quickly, accurately and reliable as to preventing an erroneous dose of medication.

Safety system for an electrically driven medical delivery device and a computer-readable medium

The invention relates to: A medication delivery device and a method of making such a device. The object of the present invention is to provide a handy medication delivery device that may be easily adjusted to the different needs of a given user in different situations and to the different needs of different users, and which is economic from a production point of view. The problem is solved in that it comprises a basis module () and one or more replaceable modules (), each of which is adapted to cooperate mechanically and/or electronically with the basis module to provide a specific function, and the basis module includes resources that are jointly used by the replaceable modules. This has the advantage of providing a rational concept for economically supplying high quality, mass-produced devices capable of being customized to individual users' needs for functionality by avoiding the duplication of key components. The invention may be used in injector type, medication pump type, inhaler or spray type devices for delivering a discrete dose or a continuous dose of a medication to a user.

Medication delivery device with replaceable cooperating modules and a method of making same

A dose setting device for a delivery system has a piston rod ( ) which successively presses a piston ( ) into a cylinder ampoule ( ). Doses are set by rotating a second part ( ) of the piston rod ( ) in relation to a first part ( ). The two parts are connected by mating threads so that the total length of the piston rod ( ) is increased proportional to the angle of rotation, and a point ( ) on the second part is moved away from a stop position fixed in relation to a housing ( ) The set dose is delivered when the point ( ) is moved back to the stop position. The first part ( ) can be axially displaced but not rotated in the housing ( ), and the second part ( ) can both rotate and be axially displaced. The first part ( ) is maintained in abutment with the piston ( ) and the second part ( ) is coupled to be rotated by a dose setting wheel ( ). An injection push button ( ) is movable between a projecting position and a pressed home position and has elements ( ) acting on the second part ( ) to press this part to its stop position.

Dose setting device

A disposable lancet combined with a reagent carrying strip which carries a reagent that indicates the concentration of a blood component in a blood sample placed in contact with the strip. The reagent carrying strip is connected to the lancet, e.g. by molding. One end of the lancet is sharpened for piercing the skin. The strip is sheet-like and has a first side and a second side, which sides are both accessible for the user, such that the reagent carrying strip can be inserted into a blood glucose meter. A weakened tear line is provided at a connection between the lancet and an edge of the reagent carrying strip so that the reagent carrying strip may be easily disconnected from the lancet.

Disposable lancet combined with a reagent carrying strip and a system for extracting and analyzing blood in the body utilizing such a disposable lancet

The invention relates to: A portable medication delivery device ( ) comprising a medication cartridge ( ) having an outlet ( ) and a movable piston ( ), and a housing ( ) for holding said cartridge, and a flexible piston rod ( ) being operable to engage and displace said piston along an axis ( ) of said cartridge, and guiding means ( ) for bending said piston rod away from said axis, and actuating means ( ), and driving means ( ) for transferring movement from said actuating means to said piston rod, said driving means including a driving wheel ( ) for displacing the piston rod ( ), said flexible piston rod comprising regularly spaced first members ( ) adapted to mechanically cooperate with corresponding second members ( ) on said driving wheel. The object of the present invention is to provide a medication delivery system that combines compactness with an improved accuracy. The problem is solved in that said flexible piston rod ( ) exhibits a linear or approximately linear path between said driving wheel ( ) and said piston ( ). This has the advantage of yielding a compact, low-weight device with an improved dose accuracy. The invention may e.g. be used in injection or infusion devices for a person's self-treatment of a disease such as diabetes.

Medication delivery device with bended piston rod

A flexible piston rod for an injection device, which piston has the form of a helical spring made from a number of narrowly adjacent turns of windings. These turns provide an external thread fitting into the internal thread of a nut element. When the nut element is rotated, the piston rod is advanced forward, which movement is used to displace a piston inside a cartridge containing a fluid to be expelled. In order to prevent the piston rod from rotating when the nut element is rotated, the helical spring making up the piston rod is provided with a longitudinal spine, which is located at a peripheral area of the helical spring.

Flexible piston rod

An injection device has signal generators (,) which are connected to operative elements (,) of the device and which give off signals which represents the operative condition of the device. The signals are sent to an electronic circuit which controls a presentation of the operational condition of the device and presents operational conditions, which are defined as not allowed, as error indications by switching off the display presenting the operational condition of the device. The number of signals from each generator is counted and a number of operations exceeding a pre-set number for the signal generator in question is interpreted as representing a not allowed operational condition.

Injection device with electronic presentation of set doses

An injection system for preparing a mixture of a solvent and a medicament and for subsequent dosed injection of the mixture comprises a syringe accommodating an ampoule (,) in which a liquid is stored between a membrane (,) dosing one end of the ampoule (,) and a piston (,) which can by a piston rod (,) be forced into the ampoule (,) to press out a dose of the liquid. The piston rod (,) and the piston (,) has mutual engaging threads (,) by which the piston (,) is coupled to the piston rod (,) to follow this rod in both axial directions. An outer thread (,) engaging an inner thread (,) in a housing is provided on a part (,) of the piston rod (,) so that rotation of the piston rod (,) will screw this rod and the piston (,) into the ampoule (,). A detent (,) ensures that the piston rod (,) is only rotated in a dose administering direction. However, the thread (,) of the piston rod (,) can be disengaged from the thread (,) of the housing to set the piston rod (,) free to be moved in a proximal direction.

Growing community of inventors

Gentofte, Denmark

Lars Peter Klitmose