Foss Electric A/s

Lattec I/s

Lars Nygaard

Per Waaben Hansen

Borkur Arnvidarson

A method of preparing a dry stick test device for determining an analyte in a milk sample by chemical assay. At least one reagent pad is provided by impregnating a first porous material with an aqueous solution including a reagent capable of reacting with the analyte, a derivative of the analyte or an indicator compound for the analyte to provide a detectable signal when in a moistened state. The reagent pad is dried. A development pad is provided by impregnating a second porous material with an aqueous solution including at least one controlling compound which, when in a moistened state, is capable of providing a condition required for the reagent to react with the analyte to provide the detectable signal. The impregnated second porous material is dried. The first porous material is immobilized with the second porous material, on a solid support, to obtain the dry stick test device.

Dry stick device and method for determining an analyte in a sample

The present invention relates to a dry stick test device for the determination of an analyte in a sample by means of a chemical assay. The device comprises: (i) optionally a solid support, (ii) at least one reagent pad comprising a reagent capable of reacting with the analyte, a derivative of said analyte or an indicator compound for said analyte to provide a detectable signal when in moistened state, and (iii) a development pad which is located in contact with the at least one reagent pad, optionally between the solid support and the at least one reagent pad, said development pad comprises at least one controlling compound capable of providing a condition required for the reagent to react with the analyte to provide a detectable signal, wherein the at least one reagent pad and the development pad are arranged to avoid precipitation of sample component(s) on the top-face of the device.

A method for correcting the settings of a flow cytometer, designed for fast sample handling and counting, allowing about 500 samples per hour to be counted. The counting is based on the provision of data representing a PHA diagram (Pulse Height Analysis) of registered pulses, each indicating a passed cell or particle. To check the settings the user measures a standard sample of uniform microbeads on the flow cytometer, and inserts information on a disk in a computer arranged to process the measured data and to calculate: a plurality of particle counts on the same sample, a mean count, a standard deviation s and/or Coefficient of Variation CV, a signal mean value SM, a signal width (width of the bell-curve in the PHA-diagram). The parameters are compared to pre-set limits ( ) and the PHAS curve is compared to an ideal curve PHA A user help program for adjusting the flow cytometer is arranged to display typical symptoms on a computer screen, to indicate the possible defects and to recommend actions to remedy the problems, based on information in a library stored in the computer. Thereby a visit by a service engineer can often be avoided.

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Græsted, Denmark

Lars Nygaard