Ut-battelle, Inc.

Evonik Degussa Gmbh

Alliance for Sustainable Energy, LLC

Technische Universitat Dortmund

University of Stuttgart

Rheinisch-westfaelische Technische Hochschule (rwth) Aachen

Amlika Mercantile Private Limited

Rheinisch-westfaelische Technische Hochshule Aachen (rwth)

Rheinisch-westfalische Technische Hochschule Aachen

Lars Mathias Blank

Andreas Schmid

Till Tiso

Thomas Haas

Harald Haeger

Gregg Tyler Beckham

Mary Ann Franden

Wolfgang Buckel

Thorsten Eggert

Andreas Karau

Steffen Howitz

Volker Sieber

Harald Häger

Nick Johannes Petrus Wierckx

Peter Welters

Katrin Grammann

Guido Jach

Bruno Buehler

Andrea Weckbecker

Katrin Schullehner

Bruno Bühler

Frederik Sven Ole Fritzsch

Michael Boelker

Bernd Lalla

Andreas Mueller

Janosch Alexander Klebensberger

Sandra Hartmann

Andrea Germer

Nick Wierckx

Wing-Jin Li

Elena Geiser

Bernhard Hauer

Lahiru N Jayakody

Nicholas S Cleveland

William E Michener

Frank Rosenau

Susanne Wilhelm

Jason Michael Whitham

Andreas Wittgens

Benjamin Kuepper

Eva Maria Del Amor Villa

Rolf Wichmann

Christian Nowacki

Jonas Johannes Christ

Michael BÖLKER

Elena Von Helden

Andreas MÜLLER

Presented herein are genetically engineeredstrains capable of metabolizing ethylene glycol and producing polyhydroxyalkanoates.

Genetically engineeredstrains capable of metabolizing ethylene glycol and its metabolic intermediates

The present invention relates to a host cell comprising an rhlA gene or an ortholog thereof that is capable of producing hydroxyalkanoyloxy alkanoic acid (HAA) and achieving an HAA concentration of more than 1 g Lwhen cultured. The invention further relates to methods of producing such a host cell and to the use of said host cell for producing HAA. The present invention also relates to methods of producing HAA using said host cell, HAA compositions produced by these methods, as well as methods of producing fatty acid compositions, fatty alcohol compositions, or hydrocarbon compositions comprising producing HAA using said host cell, and fatty acid compositions, fatty alcohol compositions, or hydrocarbon compositions produced by said methods.

Extracellular production of designer hydroxyalkanoyloxy alkanoic acids with recombinant bacteria

The present invention relates to a method of producing itaconic acid. Further the present invention relates to nucleic acids encoding an aconitate-delta-isomerase (ADI) and trans-aconitate decarboxylase (TAD) and uses of such nucleic acids. Provided is additionally a recombinant host cell engineered to overexpress nucleic acids of the present invention. Furthermore an expression cassette and a vector are provided which include the respective nucleic acid.

Means and methods for itaconic acid production

Provided is a host cell comprising a rhlA gene or an ortholog thereof, under the control of a heterologous promoter and a rhlB gene or an ortholog thereof, under the control of a heterologous promoter. The host cell is capable of achieving a carbon yield of more than 0.18 Cmol rhamnolipid/Cmol substrate. Provided is also a method of producing rhamnolipids, employing such a host cell.

Means and methods for rhamnolipid production

The invention relates to a method for the separation of a polarizable bioparticle comprising the steps: a) dielectrophoretic preseparation of a polarizable bioparticle from a suspension of bioparticles; b) fluidic separation of the selected bioparticle by fixing the bioparticle in a dielectrophoretic field cage and circulating fluid around the bioparticle; c) transferring the separated bioparticle from the dielectrophoretic field cage to a culture chamber; d) dielectrophoretic fixing of the separated bioparticle in the culture chamber and study, observation, manipulation and/or culturing of the separated bioparticle. The invention further relates to a microfluidic system and use thereof.

Method for the separation of polarizable bioparticles

The present invention relates to a cell, which has been genetically modified relative to its wild type, so that in comparison with its wild type it is able to produce more &#x3c9;-aminocarboxylic acids, more &#x3c9;-aminocarboxylic acid esters or more lactams derived from &#x3c9;-aminocarboxylic acids, starting from carboxylic acids or carboxylic acid esters. Furthermore, the present invention relates to a method for the production of a genetically modified cell, the cells obtainable by this method, a method for the production of &#x3c9;-aminocarboxylic acids, of &#x3c9;-aminocarboxylic acid esters or of lactams derived from &#x3c9;-aminocarboxylic acids, the &#x3c9;-aminocarboxylic acids, &#x3c9;-aminocarboxylic acid esters or lactams derived from &#x3c9;-aminocarboxylic acids obtainable by this method, a method for the production of polyamides based on &#x3c9;-aminocarboxylic acids or based on lactams and the polyamides obtainable by this method.

&#x3c9;-Aminocarboxylic acids, &#x3c9;-aminocarboxylic acid esters, or recombinant cells which produce lactams thereof

Growing community of inventors

Dortmund, Germany

Lars Mathias Blank