Amgen Inc.

Biovitrum Ab

Other

Lu License Ab

Genase Therapeutics B.v.

Northcone Ab

Scania Cv Ab

Lars Johansson

Christopher Harold Fotsch

Michael D Bartberger

Christopher Michael Tegley

Qingyian Liu

Guolin Cai

Qi Huang

Chester Chenguang Yuan

Nianhe Han

Randall W Hungate

Aiwen Li

David Joseph St Jean, Jr

George Moniz

Evert Homan

Meredith Williams

Bengt H Warell

Marianne Nilsson

Tobias Koolmeister

Rune Ringom

Martin Henriksson

Eric A Bercot

Matthew J Frizzle

Martin Haraldsson

Kurt A Lundstrom

Lori Sutin

Sonia Lain

Ulrika Yngve

Lars Sandberg

Teresa L Marshall

David St Jean

Ingeborg Van Leeuwen

Catherine Drummond

Johan Flygare

Björn Nilsson

A Pedar Svensson

P O Wallin

Ake P Svensson

Per Olov Wallin

Fredrik Moberg

Peter Larsson

Thomas Lundbäck

Katrina Flyrén

Zemichael Yitbarek

Carmen Medina

John Shilvock

Johan Angbrant

Teresa Sandvall

Marie Wiik

The present invention relates to the use of CDK8 and/or CDK19 inhibitors in the treatment of ribosomopathies as well as conditions characterized by reduced number of hematopoietic stem cells and/or progenitor cells; and bone anabolic disorders.

Compounds for treatment of hypoproliferative disorders

There is herein provided a compound of formula I (I) or a pharmaceutically acceptable salt thereof, for use in the treatment of cancer and/or the treatment or prevention of a viral infection, wherein A, A, L, R, Rand n have meanings as provided in the description. 

Tetrahydroindazoles and medical uses thereof

A pole arrangement comprising: &#x2014;a pole () with a tubular external wall () of sheet metal; &#x2014;a foundation () with a cavity () for receiving a lower section () of the external wall () of the pole; &#x2014;a wedge element () for securing the pole in the cavity by wedging; and &#x2014;a reinforcement element () mounted to a part of the section () of the external wall () of the pole received in the cavity, in order to counteract buckling of this part. The wedge element bears against the external wall of the pole through supporting projections, wherein there are free spaces between the supporting projections in order to allow parts of the external wall of the pole to be pressed into some of these spaces when the external is buckled in connection with a collision. The reinforcement element () is arranged at an axial distance from an upper opening () of the cavity in order to allow, in connection with a collision against the pole, buckling of the part of the external wall of the pole located between the reinforcement element and the opening of the cavity.

Pole arrangement

The present invention relates to compounds with the formula (I), (II), (III) or (IV): 

Inhibitors of 11-&#x3b2;-hydroxy steroid dehydrogenase type 1

The present invention relates to thiazolinones and also to pharmaceutical compositions comprising the compounds, as well as methods of use of the compounds for treatment of disorders associated with human 11-&#x3b2;-hydroxysteroid dehydrogenase type 1 enzyme and for the preparation of a medicament which acts on the human 11-&#x3b2;-hydroxysteroid dehydrogenase type 1 enzyme.

Inhibitors of 11-beta-hydroxysteroid dehydrogenase type 1

Compounds of formula I and IV are described and have therapeutic utility, particularly in the treatment of diabetes, obesity and related conditions and disorder: wherein the variables A-B, R, R, m, and Q are described herein.

Substituted azole aromatic heterocycles as inhibitors of 11&#x3b2;-HSD-1

Arrangement for a switchboard desk

An adjustable switchboard desk has a top which can be raised and lowered by at least two telescopic legs. In each telescopic leg a hydraulic cylinder and its associated piston are arranged. The cylinder is fixed to the desk-top and the piston is fixed to an outer part of the telescopic leg, or vice versa. The inner and outer parts of the respective telescopic legs are made of closed profile with longitudinally extending, mutually co-acting guide surfaces.

Arrangement for a desk comprising a desk-top which can be raised and

Growing community of inventors

Stockholm, Sweden

Lars Johansson