Abbott Laboratories Corporation

Other

Texas Instruments Corporation

Larry W Moore

William J Kanewske, Iii

Richard R Martin

B Jane Smith

Gilbert Clift

James E Mitchell

Kendall B Hendrick

John M Clemens

David A Yost

James A Vaught

Peter A Lagocki

Apparao Tayi

Edna S Walker

Charles D Pennington

Frederick L Clark

Douglas D McDowell

William D Rumbaugh

Donny R Walker

Kevin M Cloonan

Richard L Vickstrom

William E Watkins, Iii

Robert A Wohlford

Frederic L Clark

Richard A Merriam

Gary E Winter

David B Hills

William J Raymoure

Linda S Schmidt

Paul R Schrier

Adrian M Spronk

Carl M Oleksak

Robert B Hance

Alyn K Stanton

Keith M Lingenfelter

Robert Case

Joseph A Rice, Jr

Robert C Donald, Jr

Palmer L Tag

Patrick B Wallace

David B Carr

William J Iii Kanewske

William E Iii Watkins

Donny Ray Walker

Jane B Smith

Beverage container

A sample container segment assembly for use in an automated, continuous, and random access analytical system is disclosed. The assembly includes a sample container which is received by a sample container segment, and the sample container segment is received on a carousel of the automated analytical instrument. The test sample container includes an upper skirt and a body having a reservoir for receipt of the test sample. The segment includes a base, a frame, and a handle. The frame has a shelf for which the upper skirt of the test sample container rests on, and has openings for receipt of the body of the sample container. The carousel has a carousel trough for receipt of the base of the sample container segment, and has a plurality of alignment pins disposed in the carousel trough. The base of the sample container segment has a circular slot and an elongated slot for receiving the alignment pins and positioning the sample container segment relative to the carousel. The sample container segment can include a liquid level sensing sleeve which is made of a conductive material and surrounds the reservoir of the test sample container inserted therein. Alternatively, the test sample container can have a conductive core which surrounds the reservoir and extends therebelow. The container sample segment can also include various sleeves, or springs and arms, for securing and positioning the test sample container within the sample container segment.

Sample container segment assembly

A liquid heater assembly including a heater body having therein a coiled tube for passing liquids, a pair of heating elements, a thermistor, a thermostat, and a backup thermostat. Liquid enters the coiled liquid tube at an inlet end and exits the coiled liquid tube at an outlet end. The coiled liquid tube is positioned within the heater body between the pair of heating elements. The outlet end extends below a planar surface of the heater body. The thermistor detects the temperature changes of the heater body. The resistance of the thermistor is used to regulate the supply of power to the heating elements. The thermostat and the backup thermostat are connected in series between the power source and the heating elements to provide a safety shutoff when the heater body reaches a predetermined overheat temperature. The heater body is maintained at a predetermined temperature by regulating the electrical current to the heating elements. A receptacle can be placed in close proximity below the outlet end to minimize the air gap between the two parts. Liquid passing through the heater assembly can be delivered at a precise temperature to the receptacle below the heater assembly.

Liquid heater assembly with a pair temperature controlled electric

An apparatus for storing both coffee and nested stacks of cup-shaped coffee filters, and then automatically filling individual filters with selected amounts of coffee. Through a series of gears, an electric motor rotates an elastic projection against the topmost filter in the stack, dragging it beneath a coffee storage receptacle. Simultaneously, a rotating coffee dispenser fills with a selectable quantity of coffee and then dumps the coffee into the filter. The apparatus also includes a stirring device for insuring the stored coffee falls to the bottom of the coffee receptacle.

Apparatus for storing separating and filling coffee filters

A method for verifying that an assay methodology is properly performed, that assay reagents employed possess the necessary potency for accurately performing such assay methodology, and whether or not test samples or assay reagents have been tampered with or are adulterated, is described. The method is performed by employing an assay verification sample, comprising a positive analyte component and the test sample under analysis, wherein the assay verification sample is analyzed employing the same assay reagents and essentially the same assay methodology employed to analyze the test sample. The method is particularly useful for performing heterogeneous immunoassays on an automated continuous and random access analytical system.

Assay verification control for an automated analytical system

A method and apparatus for washing clinical apparatus is disclosed. The apparatus is a device for washing clinical apparatus, wherein the clinical apparatus is employed, at different times, to contain a first test substance during a first testing step and a second test substance during a second testing step subsequent to the first testing step. The apparatus comprises a device for supplying a wash solution to the apparatus, and for varying the quantity of the wash solution supplied to the apparatus. The apparatus further comprises a control unit for controlling the device for varying quantity to vary the quantity of the wash solution in proportion to the potential for contamination between the first test substance and the second test substance contained in the apparatus.

Apparatus and method for washing clinical apparatus

A reaction vessel having a platform and a plurality of wells extending below the platform from openings in the platform. A support skirt extending below the platform by an opening therein, secures a cuvette to the reaction vessel. At the rear of the reaction vessel, a reaction vessel tab is disposed below the reaction vessel for facilitating transport of the reaction vessel through the automated analytical system.

Reaction vessel

The present invention is a method for opening and closing a cap pivotally mounted on a container for storing reagents for use in an automated analytical instrument. The cap has one end for sealing the container and a tab extending from the other end for pivoting the cap. The method comprises the steps of positioning a closed container adjacent an actuating device mounted on the analytical system. The method further comprises the steps of projecting the actuating device against the top of the tab to pivotally open the cap to a position sufficiently vertical for aspirating reagent from the container, and retracting the actuating device from the cap to a position above the pivotal mounting thereof. The method comprises the final step of causing relative motion between the cap and the actuating device so that the actuating device drags along the top of the cap pivotally closing the cap to provide a sufficient seal on the container preventing evaporation of the reagent therefrom.

Cap actuator for opening and closing a container

The present invention is a capped-closure mounted on a container for storing reagents for use in an automated analytical instrument having an actuating device mounted thereon. The capped-closure comprises a base being generally cylindrical, wherein the base has one end opening to the container and the other end having an opening through which the reagents can be aspirated. The capped-closure further comprises a lever assembly pivotally mounted on the base. The lever assembly has one end which forms a cap operable to seal the opening the base sufficiently tightly to prevent evaporation from the container. The other end of the lever assembly forms a tab operable to pivot the lever assembly to a substantially perpendicular position with opening of the base when depressed for exposing the opening of the base to a device for aspirating the reagent from the container. The capped-closure finally comprises spring mechanism connected between the base and the lever assembly for urging the lever assembly to the substantially perpendicular position.

Capped-closure for a container

A cartridge feeder for dispensing a plurality of cartridges in single order and in upright position, each cartridge being cylindrical shape and having a top end tapering to an aperture therein and a substantially flat bottom end. A hopper stores a plurality of the cartridges and feeds those cartridges to a throat in a bridge to which the hopper is connected. The cartridge is passed through the bridge throat and to the throat of a shuttle. A pair of axially positioned pins with opposing cups close against the top end and the bottom end of the cartridge. The shuttle moves from a location underneath the bridge to a location over a chute. When the shuttle is over the chute, the first and second pins separate releasing the cartridge to fall through the chute. The first and second pins have a profile which engage the cartridge in a manner causing the bottom end of the cartridge to always drop first. The cartridge passes through the chute to a trap door. The trap door releases the cartridge to an opening in a carousel below, and positions the cartridge within the carousel by a flange mounted to the underneath side of the door.

Meia cartridge feeder

An automated, continuous and random access analytical system, having apparatus and methodology capable of simultaneously performing multiple assays of liquid samples using different assay methodologies, and providing continuous and random access while performing a plurality of different assays on the same or different samples during the same time period, is disclosed. A method is also disclosed of operating an automated continuous and random access analytical system capable of simultaneously effecting multiple assays of a plurality of liquid samples wherein scheduling of various assays of the plurality of liquid samples is followed by creating a unit dose disposable and separately transferring a first liquid sample and reagents to a reaction vessel without initiation of an assay reaction sequence, followed by physical transfer of the unit dose disposable to a processing workstation, whereby a mixture of the unit dose disposable reagents and sample are achieved during incubation. The system is capable of performing more than one scheduled assay in any order, and assays where more than such scheduled assays are presented. The automated, continuous and random access analytical system is also capable of analyzing the incubated reaction mixtures independently and individually by at least two assay procedures.

Automated continuous and random access analytical system

Apparatus and methods for analyzing fluid such as blood serum. A probe used for transferring some of the fluid to a testing station causes a change in circuit capacitance when the probe contacts the fluid. This change in capacitance causes production of a control signal which effects cessation of the descent of the probe into the fluid.

Apparatus and methods for analyzing fluids

Growing community of inventors

Plano, TX, United States of America

Larry W Moore