Metabolix, Inc.

X-body, Inc.

Sru Biosystems, Inc.

Bioscale, Inc.

Lara Madison

Gjalt W Huisman

Oliver P Peoples

Peter Li

Lance Gavin Laing

Bo Lin

Timothy Smith

Christine C Genick

William C Karl

John Gerstenmaier

Brett P Masters

Michael Francis Miller

Jaime E Arenas

Wayne U Wang

William Matthew Dickerson

Hyun-Goo Choi

Sarah Beth Hembree

The invention provides methods of detecting a change in cell growth patterns, methods of screening many different antibodies in one receptacle, and methods of detecting specific binding of an antibody to a protein or cell, wherein the antibody is in a mixture of many different antibodies.

Methods for screening cells and antibodies

The technology provided herein generally relates to reusable detection surfaces and methods for reusing a detection surface after using the detection surface in an assay for an analyte.

Reusable detection surfaces and methods of using same

The invention provides methods for detecting interactions between phage and antigen or antigen and antibody using biosensors.

Real time binding analysis of antigens on a biosensor surface

Methods for engineering transgenic organisms that synthesize polyhydroxyalkanoates (PHAs) containing 3-hydroxyhexanoate as comonomer have been developed. These processes are based on genetically engineered bacteria such asor in plant crops as production systems which include PHA biosynthetic genes from PHA producers. In a preferred embodiment of the method, additional genes are introduced in wild type or transgenic polyhydroxybutyrate (PHB) producers, thereby creating new strains that synthesize 3HH monomers which are incorporated into PHAs. The 3HH monomer preferably is derived in microbial systems using butanol or butyrate as feedstocks, which are precursors of 3-hydroxyhexanoyl-CoA. Pathways for in vivo production of butyrol-CoA specifically encompassing butyryl-CoA dehydrogenase activity are provided.

Transgenic systems for the manufacture of poly(2-hydroxy-butyrate-co-3-hydroxyhexanoate)

Transgenic systems for the manufacture of poly (3-hydroxy-butyrate-co-3-hydroxyhexanoate)

Growing community of inventors

Bridgewater, MA, United States of America

Lara Madison