Smithkline Beecham Corporation

Glaxosmithkline LLC

Smithkline Corporation

Glaxosmithkline Intellectual Property (no.2) Limited

Vitae Pharmaceuticals, Inc.

Lara Kallander

Scott Kevin Thompson

Chun Ma

James S Frazee

Michael J Neeb

Joseph Marino

Brian Griffin Lawhorn

Ajita Bhat

Joanne Philp

David A Claremon

Dennis Lee

Hilary Schenck Eidam

Guosen Ye

Ryan Michael Fox

Paul G Spoors

Joseph P Marino, Jr

Mark A Hilfiker

Robert A Stavenger

Marlys Hammond

Tram H Hoang

David G Washburn

Sarah E Dowdell

Sharada Manns

John Jeffrey McAtee

Ning Wang

Mark Elban

Disclosed are compounds having the formula: wherein R1, R2 and R3 are as defined herein, and methods of making and using the same, including use as inhibitors of BMP1, TLL1 and/or TLL2 and in treatment of diseases associated with BMP1, TLL1 and/or TLL2 activity.

Hydroxy formamide derivatives and their use

Disclosed are compounds having the formula: wherein R, R, R, R, R, Rand Rare as defined herein, and methods of making and using the same. 

Quinazoline compounds

Disclosed is a process for the preparation of a tetrahydropyran-di-amine represented by Structural Formula (I): wherein R1 is H or alkyl and E is H or an amine protecting group. 

Process for the preparation of renin inhibitors

Disclosed is a compound of having the formula:  pharmaceutically acceptable salts or solvates thereof and pharmaceutical compositions containing the same, wherein the structural variables are as defined herein. The compounds, salts and solvates of this invention are useful as LXR agonists.

Acid and ester compounds and methods of using the same

Disclosed is a compound having the formula: 

Compounds and methods

Disclosed is a compound of having the formula: 

Disclosed is a compound having the formula (I) pharmaceutically acceptable salts or solvates thereof and pharmaceutical compositions containing the same, wherein the structural variables are as defined herein. The compounds, salts and solvates of this invention are useful as LXR agonists 

Amide compounds and methods of using the same

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King of Prussia, PA, United States of America

Lara Kallander