Koninklijke Philips Corporation N.V.

University of Utah Research Foundation

Respironics, Inc.

Ric Investments, Inc.

Axon Medical, Inc.

Lara Brewer

Joseph Allen Orr

Kai Kück

Kai Kuck

Soeren Hoehne

Dwayne Ronald Westenskow

Suzanne Wendelken

Quinn Tate

Annette Macintyre

Srinath Lingutla

James Agutter

Noah Syroid

Frank Drews

Santosh Balakrishnan

Matthias Goerges

Daniel Snell

Devices, systems, and methods for measuring the blood loss of a subject during a medical procedure. Blood and other fluids are received within a container, and a blood measurement device determines the hemoglobin concentration of the fluid within the container. The blood measurement device can also calculate the estimated blood loss of the subject based upon the determined hemoglobin concentration and the volume of the fluid within the container and the patient's hemoglobin.

Devices, systems, and methods for measuring blood loss

A gas concentration monitoring system () may include a processor () configured to detect a concentration of a selected gas in a sample gas flow obtained from a physical interface () to a patient (); form a dataset including a plurality of data points, each data point corresponding to the detected concentration of the selected gas within the sample gas flow during a sampling time; group the data points according to a frequency of occurrence of the data points within the sampling time; and/or determine at least one of a signal confidence and signal quality based on relative characteristics between the groups of data points.

System for performing histogram analysis of the time-based capnography signals and method of operation thereof

A capnography system (), comprising: a controller () configured to obtain a sample gas flow from a physical interface () for a patient (); determine a change in a characteristic of the sample gas flow during a sampling time interval; determine whether the change in the characteristic of the sample gas flow during the sampling time interval is equal to or greater than a corresponding threshold value; determine that supplemental oxygen is provided when it is determined that the change in the characteristic of the sample gas flow is equal to or greater than the threshold value; and determine that supplemental oxygen is not provided when it is determined that the change in the characteristic of the sample gas flow is less than the threshold value.

Capnometry system with supplemental oxygen detection and method of operation thereof

A subject interface appliance () configured to deliver a breathable substance to a subject. The subject interface appliance includes a primary interface () configured to deliver a breathable substance to the subject, and a secondary interface () configured to obtain gas samples from the airway of the subject. The secondary interface is resiliently held at a default position with respect to the primary interface. The default position is located such that installation of the primary and secondary interfaces on the subject results in the application of a bias force to the secondary interface that holds the secondary interface in place.

Subject interface appliance and method for delivering a breathable substance to a subject while obtaining gas samples from the airway of the subject

Breaths of a subject are identified based on the concentration of carbon dioxide at or near the airway of the subject. Troughs corresponding to inhalation are identified and plateaus corresponding to exhalation are identified. A breath is identified responsive to a trough being followed by a plateau.

System and method of identifying breaths based solely on capnographic information

Values of components of total carbon dioxide excreted by a subject can be provided. One or more signals may be received conveying information related to a rate of total carbon dioxide excreted by the subject. Based at least in part on the received one or more signals, a first capnometric component and/or a second capnometric component may be determined. The first capnometric component may indicate a rate of metabolic carbon dioxide production. The second capnometric component may indicate a rate of carbon dioxide transfer to or from body compartments of the subject that store carbon dioxide. The first capnometric component and/or the second capnometric component may be presented to a user.

Determining components of total carbon dioxide excreted by a subject

Ventilation information may be presented. Output signals may be received that convey information related to one or more breathing parameters of a subject receiving assisted or controlled mechanical ventilation. Based at least in part on the received output signals, volumetric components of a tidal volume of the subject may be determined. The volumetric components may include an alveolar dead space, an effective alveolar tidal volume, and/or other volumetric components. The alveolar dead space is the volume of inspired gas that occupies alveoli but does not take part in oxygen exchange in the lungs of the subject. The effective alveolar tidal volume is the volume of inspired gas that takes part in oxygen exchange in the lungs of the subject. A visual representation that textually or graphically represents the tidal volume, and/or textually or graphically represents the volumetric components separately from each other may be presented via a user interface.

Intuitive presentation of ventilation effectiveness

A system is configured to monitor the dead space fraction of a subject in a substantially ongoing manner, rather than only updating the dead space fraction of the subject if one or more blood gas parameters of the subject are measured. This may facilitate enhanced control over respiratory therapy being provided to the subject, may inform decisions about care of the subject, and/or may provide other enhancements.

System and method for determining dead space fraction in an ongoing manner from intermittent blood gas samples

Methods for estimating the volume of the carbon dioxide stores of an individual's respiratory tract include determining a carbon dioxide store volume at which a correlation between corresponding signals of carbon dioxide elimination and an indicator of the content of carbon dioxide in blood of the individual is optimized. The estimate of the volume of carbon dioxide stores, which comprises a model of the respiratory tract, or lungs, of the individual, may be used as a transformation to improve the accuracy of one or both of the carbon dioxide elimination and carbon dioxide content signals. Transformation, or filtering, algorithms are also disclosed, as are systems in which the methods and algorithms may be used. The methods, algorithms, and systems may be used to accurately and noninvasively determine one or both of the pulmonary capillary blood flow and cardiac output of the individual.

Methods and apparatus for improving time domain relationships between signals obtained from respiration

A basic life support system (BLSS) includes a processing element and an output element, such as a display screen or an audio output element, for providing an individual with real-time instructions on providing emergency medical care to a patient until paramedics or other healthcare professionals arrive to take over care for the patient. The instructions may be provided as graphics, including animations, as text, audibly, or as a combination of visible and audible elements. The BLSS may be configured for providing emergency medical care to individuals who have suffered from ventricular fibrillation. Accordingly, the BLSS may also include a defibrillation apparatus, an air or oxygen supply, a respiratory interface, one or more sensors, or a combination thereof.

System for providing emergency medical care with real-time instructions and associated methods

Methods for noninvasively measuring, or estimating, functional residual capacity or effective lung volume include obtaining carbon dioxide and flow measurements at or near the mouth of a subject. Such measurements are obtained during baseline breathing and during and shortly after inducement of a change in the subject's effective ventilation. The obtained measurements are evaluated to determine the amount of time required for exhaled carbon dioxide levels to return to normal&#x2014;effectively an evaluation of carbon dioxide 'washout' from the subject's lungs. Conversely, carbon dioxide and flow measurements may be evaluated to determine the amount of time it takes carbon dioxide to 'wash in,' or reach peak levels within, the lungs of the subject following the change in the subject's effective ventilation. Apparatus for effective such methods are also disclosed.

Noninvasive effective lung volume estimation

A differential Fick technique including a first phase in which baseline breathing parameters may be established and a second phase in which a change in the effective ventilation of a patient is induced. The durations of the first and second phases may be substantially the same and may be abbreviated relative to the durations of comparable phases of previously known differential Fick techniques. The disclosed differential Fick technique also lacks a recovery period in which the respiratory parameters of a patient are permitted to return to 'normal' levels.

Rebreathing methods including oscillating, substantially equal rebreathing and nonrebreathing periods

Algorithms, systems, and methods for estimating carbon dioxide stores, transforming respiratory gas measurements, and obtaining accurate noninvasive pulmonary capillary blood flow and cardiac output measurements

ALGORITHMS, SYSTEMS, AND METHODS FOR ESTIMATING CARBON DIOXIDE STORES, TRANSFORMING RESPIRATORY GAS MEASUREMENTS, AND OBTAINING ACCURATE NONINVASIVE PULMONARY CAPILLARY BLOOD FLOW AND CARDIAC OUTPUT MEASUREMENTS

Growing community of inventors

Bountiful, UT, United States of America

Lara Brewer