University of Pennsylvania

Lance Becker

Joshua W Lampe

Diana Bull

Devices and methods for blood flow enhancement and hemodynamic power monitoring are provided. A blood flow enhancement device includes a pump system configured to be coupled to a central vasculature of a subject during cardiopulmonary resuscitation (CPR). The pump system includes a pumping mechanism configured to increase forward blood flow generated during the CPR while substantially limiting backward blood flow generated during the CPR. The pumping mechanism being operated concurrently with the CPR. The hemodynamic power monitor is configured to control a chest compression device and an active valve.

Method for monitoring and improving forward blood flow during CPR

The invention provides systems and devices for producing two-phase coolants such as an ice slurry. Also provided are methods for producing two-phase coolants, and methods for using the two-phase coolants to lower the temperature or maintain a low temperature in any subject, system, object, device, or application where particular low temperatures are desired. Also provided are systems for determining the cooling capacity of two-phase coolants.

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Philadelphia, PA, United States of America

Lance Becker