Amino Up Chemical Co., Ltd.

Usaien Pharmaceutical Co., Ltd.

Lan Yuan

Buxiang Sun

Hajime Fujii

Takashi Nakagawa

Gen-ichiro Nonaka

Young-Joon Surh

Takehito Miura

Ken-ichi Kosuna

Gen-Ichiro Nonaka

Provided are: method of producing a sulfur-containing proanthocyanidin oligomer by reducing the molecular weight of proanthocyanidin in plants so that they can be readily absorbed through the intestine of an organism; and a health food composition and a pharmaceutical composition which contain the resultant sulfur-containing proanthocyanidin oligomer as an active ingredient and which are useful for treating and preventing various lifestyle-related diseases and brain diseases caused by generation of active oxygen species as well as for preventing aging.

Sulfur-containing proanthocyanidin oligomer composition and production method thereof

A novel substance that has the physiological activity of the aglycone of isoflavones and the physiological activity of the culture of the basidiomycetes with the physiological activities being synergistically enhanced, obtained by cultivating a basidiomycetes having a &#x3b2;-glucosidase activity in a medium containing an isoflavone, a method for producing it, and food, feedstuff and medicine containing it. The substance of the invention is improved in the physiological effect of the aglycone of isoflavones and the physiological effect of the culture of the basidiomycetes, and is not only useful as an anti-tumor agent but also is useful for therapy and/or prevention of osteoporosis and also as an immune enhancement agent.

Substance derived from basidiomycetes culture, method for producing it and its use

Sulfur-containing proanthocyanidin oligomer compositon and process for producing the same

Growing community of inventors

Hokkaido, Japan

Lan Yuan